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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein
- 保存条件:
Store at -20℃ for one year.
- 克隆性:
R013
- 标记物:
Unlabeled
- 适应物种:
见优宁维官网
- 保质期:
见优宁维官网
- 抗原来源:
见优宁维官网
- 级别:
优级
- 库存:
999
- 供应商:
Absin
- 宿主:
Rabbit
- 应用范围:
WB: 1: 1000,IHC: 1:2000
- 浓度:
0.5 mg/mL
- 靶点:
见优宁维官网
- 抗体英文名:
Rabbit anti-VDAC1 Monoclonal Antibody(R013)
- 抗体名:
Rabbit anti-VDAC1 Monoclonal mAb(R013)
- 规格:
1mL/100uL/25uL
| 规格: | 1mL | 产品价格: | 询价 |
|---|---|---|---|
| 规格: | 100uL | 产品价格: | ¥2100.0 |
| 规格: | 25uL | 产品价格: | ¥600.0 |
别名:兔抗VDAC1单克隆抗体(R013)
免疫原:Recombinant protein
应用:WB: 1: 1000,IHC: 1:2000
保持条件:Store at -20℃ for one year.
使用方法:WB,IHC
标记:Unlabeled
宿主:Rabbit
反应种属:见优宁维官网
克隆性:R013
产品描述:
Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria (1). In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics (2). Homodimerization of VDAC may be a mechanism for changing mitochondrial permeability and supporting release of cytochrome c (3). In mammalian cells, there are three VDAC isoforms, VDAC1, which is the most widely expressed isoform, as well as VDAC2 and VDAC3 (4,5).
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