Rabbit anti-ENO1 Polyclonal An

别名：兔抗ENO1多克隆抗体A synthesized peptide derived from Human ENO1(Accession P06733), corresponding to amino acid residues D383-L404. WB 1:500-1:2000, IHC 1:50-1:200, IF 1:100-400, ELISA(peptide) 1:20000-1:40000, ELISA(peptide) 1:20000-1:40000Store at -20 °C for one year. Avoid repeated freeze/thaw cyclesWB,IHC,IF,ELISA见优宁维官网RabbitHuman;Mouse;Rat

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产品描述：

Enolase is an important glycolytic enzyme involved in the interconversion of 2-phosphoglycerate to phosphoenolpyruvate. Mammalian enolase exists as three subunits: enolase-1 (α-enolase), enolase-2 (γ-enolase) and enolase-3 (β-enolase) that can form both homo- and heterodimers. Expression of the enolase isoforms differs in a tissue specific manner (1). Enolase-1 plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen receptor during tissue invasion (2,3). Abnormal expression of enolase-1 is associated with tumor progression in some cases of breast and lung cancer (4-7). Alternatively, an enolase-1 splice variant (MBP-1) binds the c-myc promoter p2 and may function as a tumor suppressor. For this reason enolase-1 is considered as a potential therapeutic target in the treatment of some forms of cancer (8).

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