Human NRG1-β1

整合素家族迟现抗原组(β1组)

整合素家族迟现抗原组 ( β 1 组 )       β1(CD29)整合素亚单位可与CD49α～f(Mα1～α6)、CD51(αV)以及α7～α11分别组成VLAl～VLA6，αV61(VNR-191)，α7α1、α8βl、α9β1和α11β1整合素分子。由于最早发现的~％A-1和VLA-2分子是在用同种异体抗原或外源凝集素活化淋巴细胞后数周才出现，因此习惯称为迟现抗原(verylateanngen，VLA)。CD29表达十分广泛，包括所有的白细胞。CD29在记忆T细胞上的表达水平高于

Quantifying Aβ1–40 and Aβ1–42 Using Sandwich-ELISA

) to quantitate both Aβ1 –40 and Aβ1 –42 in soluble pools, after secretion by cultured cells into the medium or in human cerebrospinal fluid (CSF) samples, as well as in insoluble pools, as found intracellularly in cultured cells, or deposited in the brain

Electrophoretic Separation and Immunoblotting of Aβ1–40and Aβ1–42

The main protein component of the plaques found in the brains of Alzheimer’s disease patients is Aβ, a peptide of 39 to 43 amino acids (reviewed in refs. 1 and 2). Two major Aβ isoforms have been identified in the brains of affected individuals