- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K115048P
- 2025年08月20日
- ELISA;WB
- Rabbit
- Mouse;Rat;Monkey;Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human RAN
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Mouse;Rat;Monkey;Human
- 抗原来源：
Recombinant protein of human RAN
- 目录编号：
5901
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA;WB
- 浓度：
WB 1:1000-3000. ELISA 1:10000-100000.
- 靶点：
RAN
- 抗体英文名：
Anti-RAN Polyclonal Antibody
- 抗体名：
RAN;成员RAS癌基因家族
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-RAN Polyclonal Antibody |
| 中文名称 | RAN;成员RAS癌基因家族 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse;Rat;Monkey;Human |
| 预测交叉反应 | Dog;Fruitfly;Bovine;Chicken;Zebrafish |
| 应用 | ELISA;WB |
| 稀释比例 | WB 1:1000-3000. ELISA 1:10000-100000. |
| 密度 | |
| 靶标 | RAN |
| 别名 | Androgen receptor associated protein 24; Androgen receptor-associated protein 24; ARA 24; ARA24; Gsp1; GTP binding nuclear protein RAN; GTP-binding nuclear protein Ran; GTPase Ran; Guanosine triphosphatase Ran; LPS; OK/SW-cl.81; ran; RAN member RAS oncogene family; RAN_HUMAN; RanGTPase; Ras like protein TC4; Ras related nuclear protein; Ras-like protein TC4; Ras-related nuclear protein; RASL2 8; TC 4; TC4; |
| 背景说明 | RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions; it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which; in turn; induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy’s disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR; and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy’s disease. |
| Swiss Prot | P62826 |
| Gene ID | 5901 |
| 亚细胞定位 | Nucleus Cytoplasm Secreted |
| 免疫原 | Recombinant protein of human RAN |
| Public Immunogen Range | 1-217aa |
| 理论分子量 | 24kDa |
| 实际分子量 | 42kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K115048P Anti-RAN Polyclonal Antibody
￥480 - 1600
