K004051P Anti-GNAS Polyclonal Antibody

K004051P Anti-GNAS Polyclonal

Antibody
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  • ¥960 - 1600
  • Solarbio|ActivAb
  • 北京
  • K004051P
  • 2025年08月20日
  • WB;IF;IP;ELISA
  • Rabbit
  • Rat;Human;Mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human GNAS

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze/thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Rat;Human;Mouse

    • 抗原来源

      A synthetic peptide of human GNAS

    • 目录编号

      2778

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      WB;IF;IP;ELISA

    • 浓度

      WB 1:500-2000. IF 1:50-200. IP 0.5μg-4μg.

    • 靶点

      GNAS

    • 抗体英文名

      Anti-GNAS Polyclonal Antibody

    • 抗体名

      AHO,C20orf45,GNAS1,GPSA,GSA,GSP,NESP,POH,SCG6,SgVI,protein ALEX

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    基本信息
    英文名称Anti-GNAS Polyclonal Antibody
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Rat;Human;Mouse
    应用WB;IF;IP;ELISA
    稀释比例WB 1:500-2000. IF 1:50-200. IP 0.5μg-4μg.
    密度
    靶标GNAS
    别名AHO,C20orf45,GNAS1,GPSA,GSA,GSP,NESP,POH,SCG6,SgVI,protein ALEX
    背景说明This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
    Swiss ProtO95467,P63092,P84996,Q5JWF2
    Gene ID2778
    亚细胞定位Cell membrane By similarity; Lipid-anchor By similarity
    免疫原A synthetic peptide of human GNAS
    Public Immunogen Range1-100aa
    理论分子量28kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 0.02% sodium azide,50% glycerol,pH7.3.
    储存条件Store at -20℃. Avoid freeze/thaw cycles.

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