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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant protein of human HIF1AN
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Rat;Mouse
- 抗原来源:
Recombinant protein of human HIF1AN
- 目录编号:
55662
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB;IHC;IF
- 浓度:
WB 1:1000-3000. IHC 1:50-200. IF 1:50-200.
- 靶点:
HIF1AN
- 抗体英文名:
Anti-HIF1AN Polyclonal Antibody
- 抗体名:
缺氧诱导因子1,α亚单位抑制剂抗体
- 规格:
20ul/100ul/50ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 基本信息 | |
| 英文名称 | Anti-HIF1AN Polyclonal Antibody |
| 中文名称 | 缺氧诱导因子1,α亚单位抑制剂抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Rat;Mouse |
| 应用 | WB;IHC;IF |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. IF 1:50-200. |
| 密度 | |
| 靶标 | HIF1AN |
| 别名 | Hypoxia inducible factor asparagine hydroxylase, Factor inhibiting HIF1, FIH 1, FIH-1, FIH1, Hypoxia inducible factor 1 alpha inhibitor, Hypoxia inducible factor 1 alpha subunit inhibitor, Peptide aspartate beta dioxygenase, DKFZp762F1811, FLJ20615, FLJ22027, HIF1N_HUMAN |
| 背景说明 | Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation. Positively regulates ASB4 activity, promoting vascular differentiation. |
| Swiss Prot | Q9NWT6 |
| Gene ID | 55662 |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | Recombinant protein of human HIF1AN |
| Public Immunogen Range | 1-349aa |
| 理论分子量 | 40kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇:make an Antibody against a Peptides 下一篇:Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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