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K109834P Anti-PTGS2 Polyclonal

Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K109834P
  • 2025年08月13日
  • ELISA;IF
  • Rabbit
  • Human;Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      A synthetic peptide of human PTGS2

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze/thaw cycles.

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Mouse

    • 抗原来源

      A synthetic peptide of human PTGS2

    • 目录编号

      5743

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      ELISA;IF

    • 浓度

      IF 1:50-200. ELISA 1:1000-10000.

    • 靶点

      PTGS2

    • 抗体英文名

      Anti-PTGS2 Polyclonal Antibody

    • 抗体名

      环氧合酶2/前列腺素内过氧化物合成酶2抗体

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-PTGS2 Polyclonal Antibody
    中文名称环氧合酶2/前列腺素内过氧化物合成酶2抗体
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Mouse
    预测交叉反应Rabbit(85.7%);Horse(85.7%)
    应用ELISA;WB;IF
    稀释比例WB 1:1000-3000. IF 1:50-200. ELISA 1:1000-10000.
    密度
    靶标PTGS2
    别名COX-2;PHS II;PGH synthase 2;PGHS-2;COX2
    背景说明Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates arachidonate (AA, C20:4(n-6)) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide PGH2, the precursor of all 2-series prostaglandins and thromboxanes. This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins. The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons. Similarly catalyzes successive cyclooxygenation and peroxidation of dihomo-gamma-linoleate (DGLA, C20:3(n-6)) and eicosapentaenoate (EPA, C20:5(n-3)) to corresponding PGH1 and PGH3, the precursors of 1- and 3-series prostaglandins. In an alternative pathway of prostanoid biosynthesis, converts 2-arachidonoyl lysophopholipids to prostanoid lysophopholipids, which are then hydrolyzed by intracellular phospholipases to release free prostanoids.
    Swiss ProtP35354
    Gene ID5743
    亚细胞定位Cytoplasm
    免疫原A synthetic peptide of human PTGS2
    Public Immunogen Range180-230/604aa
    理论分子量69kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze/thaw cycles.

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

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