- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K111214P
- 2025年08月13日
- WB;IHC
- Rabbit
- Mouse;Rat;Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human EIF2S3
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Mouse;Rat;Human
- 抗原来源：
Recombinant protein of human EIF2S3
- 目录编号：
1968
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB;IHC
- 浓度：
WB 1:1000-3000. IHC 1:50-200.
- 靶点：
EIF2S3
- 抗体英文名：
Anti-EIF2S3 Polyclonal Antibody
- 抗体名：
真核翻译起始因子2亚基3抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-EIF2S3 Polyclonal Antibody |
| 中文名称 | 真核翻译起始因子2亚基3抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse;Rat;Human |
| 预测交叉反应 | Bovine;Zebrafish;Orangutan;Chicken;Rabbit;Pig |
| 应用 | WB;IHC |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| 密度 | |
| 靶标 | EIF2S3 |
| 别名 | EIF2;EIF2G;EIF2gamma;MRXSBRK;eIF-2gA |
| 背景说明 | As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis. In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation. The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing. This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP. Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B. Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage. |
| Swiss Prot | P41091 |
| Gene ID | 1968 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human EIF2S3 |
| Public Immunogen Range | 123-472aa |
| 理论分子量 | 51kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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K111214P Anti-EIF2S3 Polyclonal Antibody
￥480 - 1600
