相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the C-terminal region of human LMBR1L.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0682
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
0.5 mg/mL
- 靶点:
Q6UX01
- 抗体英文名:
Anti-LMBR1L Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-LMBR1L Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
LMBR1L (Limb Region 1 Protein Homolog-Like) is a transmembrane protein that plays a crucial role in immune system regulation and Wnt signaling modulation. It is essential for lymphocyte development, functioning as a negative regulator of the canonical Wnt signaling pathway. LMBR1L works in concert with UBAC2 and the E3 ubiquitin-protein ligase AMFR to promote ubiquitin-mediated degradation of β-catenin (CTNNB1) and the Wnt receptors FZD6 and LRP6, thereby stabilizing the β-catenin destruction complex necessary for maintaining proper CTNNB1 levels. In addition to its signaling functions, LMBR1L also serves as a receptor for lipocalin-1 (LCN1) and is capable of mediating its endocytosis, linking it to processes involving cellular uptake and trafficking.
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Choi, JH. et al. (2019) Science 364(6440):eaau0812.
技术资料暂无技术资料 索取技术资料
文献支持
Anti-LMBR1L Recombinant Rabbit Monoclonal Ab
¥860





