- ￥860
- Elucigen Biosciences
- ERB0603
- 2025年08月13日
- ICC, IHC, WB
- Rabbit
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide corresponding to the N-terminal region of human PRMT5.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
ERB0603
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
Elucigen Biosciences
- 宿主：
Rabbit
- 应用范围：
ICC, IHC, WB
- 浓度：
0.5 mg/mL
- 靶点：
O14744
- 抗体英文名：
Anti-PRMT5 Recombinant Rabbit Monoclonal Ab
- 抗体名：
Anti-PRMT5 Recombinant Rabbit Monoclonal Ab
- 规格：
25μg/100μg/500μg
| 规格： | 25μg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | 询价 |
| 规格： | 500μg | 产品价格： | 询价 |
Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyzes the symmetric dimethylation of arginine residues on both histone and non-histone proteins. This enzymatic activity plays a crucial role in regulating gene expression by modifying chromatin structure and influencing transcriptional activation. PRMT5 is particularly significant in the methylation of histone H3 at arginine residues R8 and H4 at R3, modifications associated with transcriptional repression. Beyond its role in gene regulation, PRMT5 is involved in various biological processes, including RNA splicing, signal transduction, and cell cycle progression. Its dysregulation has been implicated in several cancers, such as breast, prostate, and lung cancers, making it a potential therapeutic target in oncology.
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文献和实验该产品被引用文献
Gilbreth, M. et al. (1998) Proc. Natl. Acad. Sci. USA 95, 14781-14786.
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Anti-PRMT5 Recombinant Rabbit Monoclonal Ab
￥860
