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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the N-terminal region of human HDAC7.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0576
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
Q8WUI4
- 抗体英文名:
Anti-HDAC7 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-HDAC7 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Histone deacetylase 7 (HDAC7) is a member of the class IIa histone deacetylase family, which plays a crucial role in the epigenetic regulation of gene expression. Like other HDACs, HDAC7 functions by removing acetyl groups from lysine residues on histone tails, leading to chromatin condensation and transcriptional repression. However, HDAC7 also acts on non-histone proteins, expanding its regulatory roles beyond chromatin remodeling. HDAC7 is involved in various biological processes, including cell differentiation, apoptosis, and developmental regulation, particularly within the immune system, vascular system, and skeletal muscle. It interacts with specific transcription factors, such as MEF2, to regulate tissue-specific gene expression. Dysregulation of HDAC7 has been implicated in cancer, inflammatory diseases, and cardiovascular disorders, making it a significant target of interest in epigenetics and therapeutic development.
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文献和实验该产品被引用文献
Gregory, P.D. et al. (2001) Exp Cell Res 265, 195-202.
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Anti-HDAC7 Recombinant Rabbit Monoclonal Ab
¥860





