- ￥860
- Elucigen Biosciences
- ERB0501
- 2025年08月13日
- ICC, WB
- Rabbit
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide corresponding to amino acids surrounding phosphoserine 345 in the C-terminal region of human Chk1.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
ERB0501
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
Elucigen Biosciences
- 宿主：
Rabbit
- 应用范围：
ICC, WB
- 浓度：
0.5 mg/mL
- 靶点：
O14757
- 抗体英文名：
Anti-Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Ab
- 抗体名：
Anti-Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Ab
- 规格：
25μg/100μg/500μg
| 规格： | 25μg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | 询价 |
| 规格： | 500μg | 产品价格： | 询价 |
Chk1 is a serine/threonine kinase that plays a pivotal role in the cell cycle checkpoint control, particularly in response to DNA damage or replication stress. Upon DNA damage, Chk1 is activated through phosphorylation at Ser345, allowing it to mediate cell cycle arrest, repair DNA damage, and maintain genomic stability. This phosphorylation event helps activate downstream signaling pathways that coordinate DNA repair and protect cells from the propagation of genetic errors. Phospho-Chk1 (Ser345) is a key marker for the activation of the DNA damage response and is extensively studied for its role in cancer therapy and radiation response, as targeting Chk1 phosphorylation can enhance the efficacy of DNA-damaging treatments.
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文献和实验该产品被引用文献
Liu, Q. et al. (2000) Genes Dev 14, 1448-59.
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Anti-Phospho-Chk1 (Ser345) Recombinant Rabbit Monoclonal Ab
￥860
