- 询价
- Nebulabio
- 中国
- NBAB-191509
- 2026年01月05日
- WB
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Chk1 (Phospho Ser345) protein
- 形态：
liquid
- 克隆性：
单克隆
- 保质期：
见COA
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 应用范围：
WB
- 靶点：
Chk1 (Phospho Ser345)
- 抗体英文名：
Anti-Chk1 (Phospho Ser345) Monoclonal Antibody
- 抗体名：
抗Chk1 (Phospho Ser345)单抗
- 规格：
100ul; 500ul; 1ml
| 产品信息
品名：NebuSelect™ Anti-Chk1 (Phospho Ser345) Monoclonal Antibody
别名：CHEK1, CHK1, Serine/threonine-protein kinase Chk1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
货号：NBAB-191509
品牌：Nebulabio
规格：100ul; 500ul; 1ml
| 产品描述
NebuSelect™ Anti-Chk1 (Phospho Ser345) Monoclonal Antibody (Cat# NBAB-191509) was produced in rabbits immunized with recombinant Human Chk1 (Phospho Ser345) protein, and it reacts with Human, Mouse, Rat. This antibody is validated for WB.
| 产品属性
Product Category：Rabbit MAb
Reactivity：Human, Mouse, Rat
Specificity：Human Chk1 (Phospho Ser345)
Immunogen：Recombinant Human Chk1 (Phospho Ser345) protein
Isotype：Monoclonal Rabbit IgG
Purification：Protein A & Protein G Affinity Purification
Buffer：0.2 μm filtered solution in PBS, pH7.4, containing 0.09% Sodium azide, 50% glycerol.
Conjugate：Unconjugated
Applications：WB
Dilution：WB: 1:1000～1:5000
Storage：This liquid antibody can be stored at 2℃-8℃ for at least two weeks. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or antibody diluent, the antibody is stable for at least two weeks at 2-4℃.
For Research Use Only!
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文献和实验Methods for Studying Checkpoint Kinases Chk1
-terminal regulatory domain. Within the regulatory domain there are two residues, Serine-317 (S317) and Serine-345 (S345), which are phosphorylated in active Chk1 molecules, and subsequently dephosphorylated to inactivate Chk1 and allow mitotic entry
Mammalian CHK1 is a Ser/Thr effector kinase that plays critical roles in the DNA damage-activated cell cycle checkpoint signaling pathway downstream of ATR (ATM and Rad3-related protein kinase). This chapter is focused on describing an assay
throughout interphase but not in mitosis. The primary site for phosphorylation of cdc25 is at Ser216. Phosphorylated cdc25 binds to members of the 14-3-3 family of proteins which prevents its activation of cdc2. Chk1, a protein kinase involved in the DNA damage
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