- ￥860
- Elucigen Biosciences
- ERB0471
- 2025年08月13日
- ICC, WB, Flow
- Rabbit
- Human, Mouse, Rat (predicted)
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human di-ubiquitin linked at Lys48.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat (predicted)
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
ERB0471
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
Elucigen Biosciences
- 宿主：
Rabbit
- 应用范围：
ICC, WB, Flow
- 浓度：
0.5 mg/mL
- 靶点：
P0CG47
- 抗体英文名：
Anti-Ubiquitin K48-Specific, clone Apu2, Recombinant Rabbit Monoclonal Ab
- 抗体名：
Anti-Ubiquitin K48-Specific, clone Apu2, Recombinant Rabbit Monoclonal Ab
- 规格：
25μg/100μg/500μg
| 规格： | 25μg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | 询价 |
| 规格： | 500μg | 产品价格： | 询价 |
Ubiquitin K48-specific refers to a specific type of ubiquitin chain linkage, where ubiquitin molecules are connected through lysine 48 (K48) of the first ubiquitin. This type of ubiquitination plays a crucial role in targeting proteins for degradation via the proteasome, a process known as the ubiquitin-proteasome system (UPS). The K48-linked polyubiquitin chain acts as a signal for the recognition and degradation of misfolded, damaged, or regulatory proteins that are no longer needed by the cell. By regulating the turnover of proteins, the K48-specific ubiquitination pathway is essential for maintaining cellular homeostasis, controlling cell cycle progression, and regulating various signaling pathways. Dysregulation of K48-specific ubiquitination is associated with several diseases, including cancer, neurodegenerative disorders, and immune-related conditions.
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文献和实验该产品被引用文献
Hochstrasser, M. (2000) Science 289, 563-4.
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文献支持
Anti-Ubiquitin K48-Specific, clone Apu2, Recombinant Rabbit Monoclonal Ab
￥860
