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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the C-terminal region of human mGluR5.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Rat, Human (predicted), Mouse (predicted)
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0460
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
P41594
- 抗体英文名:
Anti-mGluR5 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-mGluR5 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Metabotropic glutamate receptor 5 (mGluR5) is a G protein-coupled receptor (GPCR) that is part of the larger family of metabotropic glutamate receptors. It plays a critical role in modulating synaptic transmission and plasticity in the brain by responding to the neurotransmitter glutamate. Unlike ionotropic glutamate receptors, which directly control ion channels, mGluR5 activates intracellular signaling pathways through G proteins, influencing various cellular processes such as the release of secondary messengers, gene expression, and neuronal excitability. mGluR5 is involved in a range of brain functions, including learning, memory, and the regulation of mood and cognition. Its dysfunction has been linked to various neurological and psychiatric disorders, including Parkinson's disease, schizophrenia, and fragile X syndrome, making it a key target for therapeutic research.
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文献和实验该产品被引用文献
Tu, J.C. et al. (1999) Neuron 23, 583-92.
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Anti-mGluR5 Recombinant Rabbit Monoclonal Ab
¥860





