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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Spark Violet™ 538 anti-human CD45
- 抗体英文名:
Spark Violet™ 538 anti-human CD45
- 供应商:
上海善然生物科技有限公司
- 保存条件:
2-8℃
- 规格:
100tests
Spark Violet™ 538 anti-human CD45 Antibody
HI30
Catalog# / Size
304082 / 100 tests
Clone
Regulatory Status RUO
Workshop IV N816
Other Names LCA, T200
Isotype Mouse IgG1, κ
Description CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte
common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma
membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling
molecule that regulates a variety of cellular processes including cell growth, differentiation, cell
cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen
receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and
other Src family kinases. CD45 non-covalently associates with lymphocyte phosphataseassociated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind
galectin-1 and to be associated with several other cell surface antigens including CD1, CD2,
CD3, and CD4.
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文献和实验,这些单抗能结合小鼠造血细胞的主要分化系细胞: T、B淋巴细胞,单核/巨噬细胞,粒细胞和红细胞。将这组试剂与Streptavidin Plus BD™ IMag Particles (557812) 联合使用,就能通过免疫磁性分离法去除小鼠骨髓造血细胞的主要分化系细胞,从而富集到造血干细胞和祖细胞(阴性片断)。 Mouse Lineage Panel(559971):(5×2ml/vial) 可分离109 Mouse骨髓细胞 1) Biotin-anti
microRNA detection platform to identify genes that are induced by IFNα in hepatoma- or melanoma-derived human tumor cell lines. Despite the enormous differences in expression levels between these models, we were able to identify microRNAs
siRNA Sequences* Template Sequences** ß-actin (1) NM_001101 972-994 aatgaagatcaagatcattgc Human HeLa View, Order View gamma-actin (1) NM_001614 8-30 aagagatcgccgcgctggtca Human
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