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Spark Violet™ 538 anti-human C

D45
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  • ¥2729.86
  • BioLegend
  • 304082
  • 美国
  • 2025年08月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Spark Violet™ 538 anti-human CD45

    • 抗体英文名

      Spark Violet™ 538 anti-human CD45

    • 供应商

      上海善然生物科技有限公司

    • 保存条件

      2-8℃

    • 规格

      100tests

    Spark Violet™ 538 anti-human CD45 Antibody
    HI30
    Catalog# / Size 
    304082 / 100 tests
    Clone
    Regulatory Status RUO
    Workshop IV N816
    Other Names LCA, T200
    Isotype Mouse IgG1, κ
    Description CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte
    common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma
    membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling
    molecule that regulates a variety of cellular processes including cell growth, differentiation, cell
    cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen
    receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and
    other Src family kinases. CD45 non-covalently associates with lymphocyte phosphataseassociated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind
    galectin-1 and to be associated with several other cell surface antigens including CD1, CD2,
    CD3, and CD4.

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