维百奥生物代理AxisPharm品牌全系列产品

 

维百奥生物代理AxisPharm品牌全系列产品

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AxisPharm是一家专业的分析服务提供商，致力于为科学研究界和工业界提供高质量的分析服务。凭借先进的仪器设备和专业的技术团队，AxisPharm在生物分析、化学分析和质量控制领域树立了良好的声誉。AxisPharm公司的产品线包括：PEG 连接子、用于药物递送的脂质、荧光染料、单击化学试剂、聚聚乙二醇，共聚物、可裂解的连接子、抗体和抗体药物偶联物ADC、ADC 有效载荷、细胞生物学试剂、脱氧核糖核酸、修饰语、探针、合成肽、目标特定链接器、硫醇反应性接头、酸反应性连接子、胺反应性连接子、羰基反应性连接子、探针、修饰符。

▍AxisPharm产品线

● PEG连接子：聚合物聚乙二醇是多分散聚乙二醇 （PEG） 聚合物，是一种从石油中提取的聚醚化合物，具有从工业制造到医药的许多应用。

● 用于药物递送的脂质：在药物递送系统中起着至关重要的作用，特别是在脂质体、脂质纳米颗粒或脂质胶束等脂质制剂中。脂质提供结构稳定性，增强药物溶解度，实现控释，并促进靶向药物递送。

● 荧光染料：也称为荧光团或荧光探针，是吸收一种波长的光并以更高波长发射的化合物，从而产生可见荧光。它们是生物学研究中的重要工具，用于标记和检测蛋白质、核酸和细胞等生物分子，从而在显微镜、流式细胞术和实时荧光定量 PCR 等应用中实现灵敏和精确的可视化。

● 点击化学试剂：具有高特异性和最少的副产物，简化了复杂的合成过程。因此，它们在分子生物学、材料科学和药物化学中发挥着至关重要的作用。

● 聚合物聚乙二醇：多分散聚乙二醇 （PEG） 聚合物，是一种从石油中提取的聚醚化合物，具有从工业制造到医药的许多应用。

● 可裂解连接子：一类重要的分子，广泛应用于药物发现、化学生物学和材料科学等各个领域。这些连接子充当两个或多个分子实体之间的连接桥，可以在特定条件下选择性地裂解，从而释放附着的分子。这一特性使它们成为生物活性化合物靶向药物递送、成像和控释的有吸引力的工具。

● 抗体及抗体-药物偶联物及细胞生物学试剂：种类丰富可选择。

● ADC有效载荷：作为 ADC 的三个主要成分之一，有效载荷是高活性和有毒的药物分子，通过化学连接子附着在抗体上。有效载荷可以是小分子、蛋白质毒素、生物活性肽、酶，甚至放射性核素。通过适当的接头与适当的载体系统耦合的有效载荷可能会显示出靶向药物递送的特异性和有效性的提高。

● 脱氧核糖核酸：DNA 是脱氧核糖核酸的缩写，是一种包含所有生物体发育和功能的遗传指令的分子。DNA 由四个基本组成部分组成，称为核苷酸，由糖、磷酸基团和含氮碱基组成。

● 改性剂：改变其他分子或材料特性的化合物。在药物研发领域，改性剂在新型药物递送系统和生物医学设备的设计和优化中发挥着至关重要的作用。一种常见的改性剂类型是官能团，它是赋予分子特定化学和物理性质的原子的特定排列。

● 探针：AxisPharm 提供各种靶标特异性探针，例如叶酸 PEG、生物素 PEG、PROTAC PEG、荧光染料探针和图像探针。探针是一类含有官能团的化合物，旨在选择性地与生物分子（如酶、受体和核酸）相互作用。这些官能团包括荧光染料、生物素和亲和标签等，可以检测和定量复杂生物系统中的特定分子。

 

Different Types of Polyethylene Glycol PEG Linkers in Stock
Acid PEG	Diketone PEG	Non-PEG linker	PFP ester PEG	Sugar PEG β-Glucuronide Linker
Aldehyde PEG	DNP PEG	PEG-t-butyl ester	Phosphonate PEG	Sulfonic acid PEG
Alkyne PEG	DBCO PEG	PEG-X-PEG	Polymer PEG	TCO PEG
Amino PEG	DSPE PEG	Peptide Linkers	Propargyl PEG	Tetrazine PEG
Aminooxy PEG	Fluorescent PEG	Lipid PEG	PROTAC Linker	Homobifunctional PEG
Azide PEG	Fmoc PEG	M-PEG	Silane PEG	Bromo PEG
BCN-PEG	Folate PEG	Maleimide PEG	SPDP PEG	Tosylate PEG
Benzyl-PEG	Thiol PEG	MeNH-PEG	Branched PEG	Bis-Sulfone PEG
Biotin PEG	Hydrazide PEG	NHS ester PEG	HyNic PEG	DOTA Reagent DOTA PEG
Bis-PEG-acid	Hydroxy PEG	Boc-PEG	Bis-PEG-NHS	Iodo PEG
Bis-PEG-NHS	Cleavable Linkers
Lipids for Drug Delivery
Biotinyl Cap PE	Dodecanyl PE	Other Lipid	Phosphatidylcholine	Phosphatidylethanolamine
Biotinyl PE	Glutaryl PE	PDP PE	Phosphoglycerol	Ptd Thioethanol
Caproylamine PE	Ionizable Lipid	PE MCC	Phosphoserine	Succinyl PE
Cationic Lipid	Lipid PEG	Cyanur PE	MPB PE
Fluorescent Dye
AF Dyes	Cyanine Dyes	MB Dyes	Rhodamine Dye	Rox (carboxy-X-rhodamine) Dye
APDye Fluors	DNP PEG	JOE	R6G	Peptide Labeling Reagents
Bodipy Probes	Fluorescein (FAM)	Pyrene Probes	TAMRA Dye	Classic Fluorescent Dyes
IR Fluors	Quenchers	Coumarin 343
Click Chemistry Tools & Reagents
Alkyne PEG	BCN-PEG	PTAD Linker	Tetrazine PEG	Click Chemistry Auxiliary Reagents
Azide PEG	DBCO PEG	TCO PEG	Methylcyclopropene Linkers
Polymer PEG
Acrylate	Biotin	Fmoc	Lipoamide	Silane
Active ester	Boc	Folate	Maleimide	Stearic acid
Aldehyde	Carboxylic acid	guanlian1010	MW 2000	TCO
Amine	Cholesterol	Hydrazide	MW 5000	Thiol
Azide	DBCO	Hydroxyl	Polysarcosine
Cleavable Linkers
-S-S-Cleavable	PC Cleavable	Disulfide Linkers	Dde Cleavable Linkers	β-Glucuronide Linkers
Cleavable Peptide	diazo biotin probes	DTSSP crosslinker	Photocleavable Biotin
Antibody and Antibody Drug Conjugate (ADC)
Inotuzumab	Trastuzumab	Enfortumab	Labetuzumab govitecan	Mirvetuximab soravtansine (solution)
Vobramitamab	Disitamab	Mirzotamab	Loncastuximab tesirine	Trastuzumab deruxtecan (solution)
Polatuzumab	Ozuriftamab	Brentuximab	Trastuzumab deruxtecan	ADC Control Human IgG1-Deruxtecan (DAR 8)
Gemtuzumab	Inebilizumab	Datopotamab	Cofetuzumab pelidotin	Glembatumumab vedotin
Daratumumab (PBS)	Denintuzumab	Sacituzumab govitecan	Belantamab mafodotin	Trastuzumab duocarmazine
Praluzatamab	Naratuximab	Tisotumab	Enfortumab vedotin-ejfv	Trastuzumab emtansine (solution)
Lorvotuzumab	Rolinsatamab	Trastuzumab emtansine	Telisotuzumab vedotin	Enfortumab vedotin-ejfv (solution)
Izeltabart	Mipasetamab	Datopotamab deruxtecan	Gemtuzumab ozogamicin	Brentuximab vedotin (solution)
Lupartumab	Iladatuzumab	ORM-5029	Cantuzumab ravtansine	Depatuxizumab mafodotin
Cantuzumab	Briobacept	Ifinatamab deruxtecan	Tusamitamab ravtansine	ADC Control Human IgG1-Deruxtecan (DAR 4)
Lonigutamab	Tamrintamab	Tisotumab vedotin	Zilovertamab vedotin	Depatuxizumab MMAE
Moxetumomab	Sacituzumab	Disitamab vedotin	Polatuzumab vedotin	ADC Control Human IgG1-vcMMAF
Azintuxizumab	Upifitamab	Belantamab	Pivekimab	Sacituzumab govitecan (solution)
Lifastuzumab	Glembatumumab	Patritumab deruxtecan	Farletuzumab ecteribulin
Payloads and Linker modified Payloads
Exatecan	Belotecan HCl	SGD-1882	Dolastatin 10	MC-Val-Cit-PAB-Doxorubicin
SN 38	Gimatecan	MMAF	Calicheamicin	Gly3-Val-Cit-PAB-MMAE
Amrubicin	Taltobulin	Auristatin E	Eribulin Mesylate	SuO-Glu-Val-Cit-PAB-MMAE
Mitomycin C	Dxd	Chlorambucil	Soblidotin (Auristatin PE)	Fmoc-G-amino-CH2O acetyl-Exetecan
Deruxtecan analog	Lurtotecan	PF-06380101	Deruxtecan analog 2	DM1-MCC-PEG3-Biotin
sulfo-SPDB-DM4	Exatecan mesylate	Auristatin F	Paclitaxel	GGFG-amino-CH2O-acetyl Exetecan
Rubitecan	MC-DM1	MMAF-methyl ester	MC-MMD10	Mal-PEG8-Val-Cit-PAB-MMAE
(4-NH2)-Exatecan	Irinotecan	Doxorubicin-SMCC	SPDB-DM4	DBCO-PEG4-Val-Cit-PAB MMAF
Topotecan	PNU-159682	MMAD	10-Hydroxycamptothecin	Topotecan Hydrochloride
CL2A-SN38	DM4	7-Ethylcamptothecin
Cell Biology Reagents
Neuro-DiO, lipophilic tracer	VU (5-Vinyl-uridine)	CM-DiI, lipophilic tracer	LumiTracker ER Green	ER-Tracker Red (BODIPY TR Glibenclamide)
Annexin V-AF 647 conjugate	DAPI, blue fluorescent nucleic acid stain	Propidium Iodide	Deep-Red Fluorescent Nissl Stain	MitoCLox, mitochondrial lipid peroxidation probe
Annexin V-AF 488 conjugate	LumiTracker Mito Rhodamine 123	LumiTracker Mito Green FM	RAPID DiI, lipophilic tracer	Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)
Annexin V, His Tag	Thiazole Orange	SynaptoProbe® Red	LumiTracker ER Red	Linear Polyacrylamide for Nucleic Acid Precipitation
DiD, lipophilic tracer	RH 237, potentiometric probe	SynaptoProbe® Green	RAPID DiO, lipophilic tracer	Fluo-4 AM, green fluorescent calcium indicator
DiR, lipophilic tracer	Hoechst 33342, blue fluorescent nucleic acid stain	LumiTracker® Mito Red FM	DiI, lipophilic tracer	YODi-1, green fluorescent nucleic acid stain
DNA
CPG solid supports	DNA Stains	Modified Triphosphates	phosphoramidite
Probes
Biotin PEG	Folate PEG	Image Probes	PROTAC Linker
Amine reactive Linkers
Acid PEG	Aldehyde PEG	Bromo PEG	Maleimide PEG	NHS ester PEG

 

▍AxisPharm提供的服务

● 蛋白质组学服务：提供质谱分析、蛋白质鉴定和定量服务。专注于生物标志物分析，帮助客户在复杂的生物样本中发现和验证潜在的生物标志物。

● 代谢组学服务：利用先进的LC-MS/MS技术进行代谢物分析，提供通路洞察，帮助客户理解代谢途径和生物过程。

● 高级LC-MS/MS服务：用于PK分析和HPLC分离，确保高精度和高效率的研究结果，提供PK/PD研究，支持药物开发和临床前研究。

 

▍AxisPharm部分产品列表

 

Cat#	Name	M.W.	Purity
AP15197	Exatecan	435.45	≥98%
AP15072	SN 38	392.4	≥95%
AP15226	Amrubicin	483.47	≥98%
AP15664	Mitomycin C	334.3	≥98%
AP15203	10-Hydroxycamptothecin	364.35	≥95%
AP15204	7-Ethylcamptothecin	376.41	≥95%
AP15210	Rubitecan	393.35	≥95%
AP15211	(4-NH2)-Exatecan	403.43	≥95%
AP15206	Topotecan	421.5	≥95%
AP15207	Topotecan Hydrochloride	425.5	≥95%
AP15202	Belotecan HCl	433.5	≥95%
AP15208	Gimatecan	447.5	≥95%
AP15227	Taltobulin	473.65	≥99%
AP15201	Dxd	493.48	≥95%
AP15209	Lurtotecan	518.56	≥95%
AP15196	Exatecan mesylate	531.55	≥98%
AP15200	Deruxtecan analog 2	579.58	≥95%
AP15205	Irinotecan	586.68	≥95%
AP15224	PNU-159682	641.62	≥98.24%
AP15220	Soblidotin (Auristatin PE)	701.98	≥95%
AP15225	SGD-1882	725.8	≥98%
AP15213	MMAF	732	≥95%
AP15216	Auristatin E	732	≥95%
AP15311	Chlorambucil	304.21	≥98
AP15219	PF-06380101	743.01	≥95%
AP15214	Auristatin F	746	≥95%
AP15215	MMAF-methyl ester	745.99	≥98%
AP15187	Doxorubicin-SMCC	762.8	≥98%
AP15217	MMAD	771.06	≥98%