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- 文献和实验
- 技术资料
- 保存条件:
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期:
1 year
- 英文名:
Recombinant Human CD111/NECTIN1 Protein, C-Fc
- 库存:
999
- 供应商:
abinScience
- 规格:
100ug

| Product name | Recombinant Human CD111/NECTIN1 Protein, C-Fc |
|---|---|
| Catalog No. | HS747021 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >95% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | Q15223 |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Alternative Names | Nectin-1, Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Herpesvirus Ig-like receptor, HIgR, Nectin cell adhesion molecule 1, Poliovirus receptor-related protein 1, CD111, NECTIN1, HVEC, PRR1, PVRL1 |
| Species | Homo sapiens (Human) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
Product categories and application fields.
Main products...
Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• Functional characterization of human CD34+ cells that express low or high levels of the membrane antigen CD111 (nectin 1)., PMID:12764381
• Engineered herpes simplex viruses efficiently infect and kill CD133+ human glioma xenograft cells that express CD111., PMID:19521665
• Hypoxia Moderates γ(1)34.5-Deleted Herpes Simplex Virus Oncolytic Activity in Human Glioma Xenoline Primary Cultures., PMID:22741039
• Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression., PMID:30224769
• Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection., PMID:12885915
• Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses., PMID:26188016
• Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumors., PMID:24497984
• Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus., PMID:15110526
• Role for plasmacytoid dendritic cells in the immune control of recurrent human herpes simplex virus infection., PMID:19073735
Nectin-4 ADC成功之后,NECTIN家族还有哪些“宝藏成员”?
-2、Nectin-3、Nectin-4;’Necl亚群包括:Necl-1、Necl-2、Necl-3、Necl-4、Necl-5。各成员在不同研究领域中存在多种命名方式,下表汇总了各成员的常用别名(含蛋白名称、基因旧称及其他数据库编号),以便检索和文献查阅。 家族成员 别名 Nectin-1 CD111, HVEC, HLGR, PRR1, PVRL1 Nectin-2 CD112, HVEB, PRR2, PVRL2, PVRR2 Nectin
Assessing Fc Glycan Heterogeneity of Therapeutic Recombinant Monoclonal Antibodies Using NP-HPLC
Recombinant monoclonal antibodies (rMAbs) are becoming major human therapeutics to treat life-threatening diseases such as cancer. These rMAbs are produced using either in vitro cell culture processes or transgenic technology in animals
human E-cadherin-IgG Fc domain fusion protein (E-cad-Fc) has recently been shown to be extremely efficient in facilitating the culture of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells under completely defined conditions
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