- ￥1868
- abinScience
- France
- HA633012
- 2026年03月03日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期：
1 year
- 英文名：
Recombinant Human MLLT3 Protein, N-His
- 库存：
999
- 供应商：
abinScience
- 规格：
100ug
| Product name | Recombinant Human MLLT3 Protein, N-His |
|---|---|
| Catalog No. | HA633012 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | P42568 |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Alternative Names | Protein AF-9; ALL1-fused gene from chromosome 9 protein; Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; YEATS domain-containing protein 3; MLLT3; AF9; YEATS3 |
| Species | Homo sapiens (Human) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
Product categories and application fields.
Main products...
Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• MLLT3 Regulates Melanoma Stemness and Progression by Inhibiting HMGB1 Nuclear Entry and MAGEA1 M5C Modification., PMID:39716999
• The Intrinsically Disordered Proteins MLLT3 (AF9) and MLLT1 (ENL) - Multimodal Transcriptional Switches With Roles in Normal Hematopoiesis, MLL Fusion Leukemia, and Kidney Cancer., PMID:34174329
• MLL-Rearranged Acute Lymphoblastic Leukemia., PMID:32350732
• Leukemia-associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis., PMID:35429189
• MLLT3 knockdown suppresses proliferation and cell mobility in human lung adenocarcinoma., PMID:39503060
• Mapping human haematopoietic stem cells from haemogenic endothelium to birth., PMID:35418685
• MLLT3 promotes proliferation of osteosarcoma cells by regulating JNK signaling., PMID:31966817
• Sustained spontaneous remission in KMT2A-MLLT3 mutated myeloid sarcoma., PMID:36930260
• Lineage switch in a pediatric patient with KMT2A-MLLT3 from acute megakaryoblastic leukemia to T cell acute lymphoblastic leukemia at the fourth relapse after allo-HSCT: with literature review., PMID:36472792
High Throughput Production of Recombinant Human Proteins for Crystallography
This chapter presents in detail the process used in high throughput bacterial production of recombinant human proteins for crystal structure determination. The core principles are: (1 ) Generating at least 10 truncated constructs
The Use of TAGZyme for the Efficient Removal of N-Terminal His-Tags
The use of affinity tags and especially histidine tags (His-tags) has become widespread in molecular biology for the efficient purification of recombinant proteins. In some cases, the presence of the affinity tag in the recombinant protein
新发现！关键分子 MLLT3 维持造血干细胞的自我更新，体外移植能力可增强 12 倍
《MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment》的研究论文。图片来源：Nature该研究通过多组学分析筛选出与造血干细胞自我更新能力密切相关的因子 MLLT3，研究人员通过敲减或过表达该基因的方式验证其维持造血干细胞自我更新的功能，并通过移植实验证实了其在维持造血干细自我更新能力方面发挥着关键的作用。机制层面，他们发现 MLLT3 通过结合转录活性位点及 H3K79me2 发挥其维持造血干细胞自我更新能力
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