- ￥1868
- abinScience
- France
- HB337012
- 2025年08月01日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期：
1 year
- 英文名：
Recombinant Human RNF4 Protein, N-GST & C-His
- 库存：
999
- 供应商：
abinScience
- 规格：
100ug
| Product name | Recombinant Human RNF4 Protein, N-GST & C-His |
|---|---|
| Catalog No. | HB337012 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | P78317 |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Alternative Names | E3 ubiquitin-protein ligase RNF4; 2.3.2.27; RING finger protein 4; Small nuclear ring finger protein; Protein SNURF; RNF4; SNURF; RES4-26 |
| Species | Homo sapiens (Human) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
Product categories and application fields.
Main products...
Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication., PMID:38530355
• RNF4 mediated degradation of PDHA1 promotes colorectal cancer metabolism and metastasis., PMID:39521913
• RNF4 controls the extent of replication fork reversal to preserve genome stability., PMID:35640614
• RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival., PMID:36153321
• Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair., PMID:37059091
• RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication., PMID:37607592
• RNF4-mediated SUMO-targeted ubiquitination relieves PARIS/ZNF746-mediated transcriptional repression., PMID:32197837
• RNF4 interacts with multiSUMOylated ETV4., PMID:28612051
• RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse., PMID:34868226
depends on product and its function. N-terminal sequencing revealed that the purified rBoNTC(Hc )-N is missing the first eight amino acids of the N-terminus of the protein, whereas the purified rBoNTC(Hc )-C protein is intact. After a mouse bioassay test
Mutational Analysis of the Human Protein C Gene
The single gene for protein C is located at position q13–q14 on chromosome 2 (1 ). Two groups have described human genomic clones of protein C isolated from phage l charon libraries using cDNA for human protein C as hybridization probes
Thrombin Cleavage of GST-Fusion protein
activity keeps the enzyme in aliquots at -80°C. Thrombin (MW 37kDa) ~4500units/mg. One unit cleaves theoretical 100ug protein in 16hr at 22°C in buffer. Another possibility is to use high purity enzyme from Sigma # T-6884: 3-10 U of thrombin can be used
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