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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 保质期：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 英文名：
Angiotensin II,human,FAM labeled
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
10mg/5mg/1mg
| 规格： | 10mg | 产品价格： | ￥6970.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥4980.0 |
| 规格： | 1mg | 产品价格： | ￥1990.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy
成员:Yingying Shi, Yu Liu, Jiaxin Huang, Zhenyu Luo, Xuemeng Guo, Mengshi Jiang, Xiang Li, Yichao Lu, Xu Liu, Xinyu Shan, Lihua Luo, Jian You
论文因子:11.6 发表期刊:Theranostics pmid:35547749
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.76622-26-9 |
| 单字母序列 | YGGFMRRVGRPEWWMDYQKRYG |
| 三字母序列 | Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly |
| 别名 | Bovine adrenal medulla-22P |
| 分子式 | C130H184N38O31S2 |
| 分子量 | 2839.25 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | opium肽(opioid peptides) |
| 规格 | BAM-22P 是一种强效的opium肽，是一种强效的opium类 (opioid) 激动剂。BAM-22P, a highly potent opioid peptide, is a potent opioid agonist. |
| In Vitro | 未检测 |
| In Vivo | Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla. Plasma levels of BAM-22P are determined by a sensitive radioimmunoassay, and the specificity of the assay is confirmed using high-performance liquid chromatography. Plasma BAM-22P levels s cholestatic rats are significantly higher than those in control rats. This increase in plasma BAM-22P levels is completely prevented by adrenalectomy. Adrenal steady-state levels of proenkephalin mRNA, as determined by Northern blot hybridization analyses, are also increased significantly in cholestatic rats. These increases in proenkephalin mRNA levels are not paralleled by changes in adrenal BAM-22P peptide levels, which are similar in cholestatic rats and their respective controls. Similar levels of proenkephalin mRNA expression are observed in innervated and denervated adrenal glands from cholestatic rats, suggesting that the increase in adrenal proenkephalin mRNA levels in acute cholestasis is not due to splanchnic nerve activation. Thus acute cholestasis in the rat is associated with adrenal secretion and accumulation in plasma of the highly potent opioid peptide BAM-22P and an augmentation of adrenal proenkephalin mRNA expression. The increase in plasma BAM-22P levels may contribute substantially to the increase in total circulating opioid activity documented in cholestatic rats. Adrenal gland levels of BAM-22P are similar in BDR and sham-resected rats (BDR, 1.10±0.39 ng/g; sham, 0.93±0.16 ng/g; NS). BAM-22P levels in ANIT-treated and oil-gavaged controls are also similar (ANIT, 2.88±0.29 ng/g; control, 2.75±0.30 ng/g; NS). However, adrenal BAM-22P levels are lower in BDR and sham-resected rats than in ANIT-treated and oil-gavaged controls (P. |
| 单位 | 瓶 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy
成员:Yingying Shi, Yu Liu, Jiaxin Huang, Zhenyu Luo, Xuemeng Guo, Mengshi Jiang, Xiang Li, Yichao Lu, Xu Liu, Xinyu Shan, Lihua Luo, Jian You
论文因子:11.6 发表期刊:Theranostics pmid:35547749
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, Howard I. Scher, and Paul Tempst Memorial Sloan-Kettering Cancer Center, New York, New York, USA 摘要： 新近研究表明，通过质谱法已建立了多种独特的血清多肽组表达模式库，而血清多肽组表达模式与临床症状密切相关。阐明血清中多肽组成的序列特征及其产生机制，将有助于将血清多肽组表达模式作为可靠的疾病标识
【专题讨论】外文文献讨论（一）---------欢迎大家积极参与、共同提高
with 1 g/ml OVA peptide (residues 323–339) in RPMI medium containing 10% FBS. Transfection For electroporations, 2.5 mol dsRNA and/or 20 g of pEGFP-N3 plasmid (Clontech Laboratories, Palo Alto, CA) were added to prechilled 0.4-cm electrode gap
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