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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 保质期：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 英文名：
Angiotensin II,human,FAM labeled
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
10mg/5mg/1mg
| 规格： | 10mg | 产品价格： | ￥6970.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥4980.0 |
| 规格： | 1mg | 产品价格： | ￥1990.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy
成员:Yingying Shi, Yu Liu, Jiaxin Huang, Zhenyu Luo, Xuemeng Guo, Mengshi Jiang, Xiang Li, Yichao Lu, Xu Liu, Xinyu Shan, Lihua Luo, Jian You
论文因子:11.6 发表期刊:Theranostics pmid:35547749
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.76622-26-9 |
| 单字母序列 | YGGFMRRVGRPEWWMDYQKRYG |
| 三字母序列 | Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly |
| 别名 | Bovine adrenal medulla-22P |
| 分子式 | C130H184N38O31S2 |
| 分子量 | 2839.25 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | opium肽(opioid peptides) |
| 规格 | BAM-22P 是一种强效的opium肽，是一种强效的opium类 (opioid) 激动剂。BAM-22P, a highly potent opioid peptide, is a potent opioid agonist. |
| In Vitro | 未检测 |
| In Vivo | Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla. Plasma levels of BAM-22P are determined by a sensitive radioimmunoassay, and the specificity of the assay is confirmed using high-performance liquid chromatography. Plasma BAM-22P levels s cholestatic rats are significantly higher than those in control rats. This increase in plasma BAM-22P levels is completely prevented by adrenalectomy. Adrenal steady-state levels of proenkephalin mRNA, as determined by Northern blot hybridization analyses, are also increased significantly in cholestatic rats. These increases in proenkephalin mRNA levels are not paralleled by changes in adrenal BAM-22P peptide levels, which are similar in cholestatic rats and their respective controls. Similar levels of proenkephalin mRNA expression are observed in innervated and denervated adrenal glands from cholestatic rats, suggesting that the increase in adrenal proenkephalin mRNA levels in acute cholestasis is not due to splanchnic nerve activation. Thus acute cholestasis in the rat is associated with adrenal secretion and accumulation in plasma of the highly potent opioid peptide BAM-22P and an augmentation of adrenal proenkephalin mRNA expression. The increase in plasma BAM-22P levels may contribute substantially to the increase in total circulating opioid activity documented in cholestatic rats. Adrenal gland levels of BAM-22P are similar in BDR and sham-resected rats (BDR, 1.10±0.39 ng/g; sham, 0.93±0.16 ng/g; NS). BAM-22P levels in ANIT-treated and oil-gavaged controls are also similar (ANIT, 2.88±0.29 ng/g; control, 2.75±0.30 ng/g; NS). However, adrenal BAM-22P levels are lower in BDR and sham-resected rats than in ANIT-treated and oil-gavaged controls (P. |
| 单位 | 瓶 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy
成员:Yingying Shi, Yu Liu, Jiaxin Huang, Zhenyu Luo, Xuemeng Guo, Mengshi Jiang, Xiang Li, Yichao Lu, Xu Liu, Xinyu Shan, Lihua Luo, Jian You
论文因子:11.6 发表期刊:Theranostics pmid:35547749
一：公司介绍 武汉明皓生物科技股份有限公司（http://www.moonbiochem.com）坐落于武汉东湖高新技术区光谷生物城, 是由一批在生命科学领域具有相当丰富经验的归国博士及经验丰富的专家共同创办的专业的生物公司。武汉明皓生物始终以“一切以客户为本”为理念，致力于为从事生命科学研究的科研人员提供高质量的化合物，多肽，蛋白及抗体产品以及高效优质的生物技术外包服务。 武汉明皓生物科技股份有限公司重在以高品质高质量为基础，以高满意度的客户服务为立命之本。我们坚信我们良好的发展
科研人必看：多肽、蛋白质、重组蛋白分不清？ 应用场景有哪些？定制如何选？
一、什么是多肽定制？ 多肽定制！是的，在科研研究中有时要根据具体需求，如特定的氨基酸序列、分子量、纯度和修饰方式等，利用化学或生物技术人工合成特定的多肽，也就是多肽定制。 二、为什么要定制多肽？ 当然是因为：有需求！ 比如： (1) 高度个性化：目录产品多肽无法满足实验需求，定制可以贴合实验需求进行设计，甚至加入同位素标记、荧光标记 (如 FITC、Cy3) 等特殊基团以追踪细胞内反应。 (2) 提高稳定性与活性：可通过特殊
, Howard I. Scher, and Paul Tempst Memorial Sloan-Kettering Cancer Center, New York, New York, USA 摘要： 新近研究表明，通过质谱法已建立了多种独特的血清多肽组表达模式库，而血清多肽组表达模式与临床症状密切相关。阐明血清中多肽组成的序列特征及其产生机制，将有助于将血清多肽组表达模式作为可靠的疾病标识
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