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- Solarbio|ActivAb
- 北京
- CLP1142
- 2025年07月30日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 保质期：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 英文名：
Corazonin
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
10mg/5mg/1mg
| 规格： | 10mg | 产品价格： | ￥7180.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥5130.0 |
| 规格： | 1mg | 产品价格： | ￥2050.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.76622-26-9 |
| 单字母序列 | YGGFMRRVGRPEWWMDYQKRYG |
| 三字母序列 | Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly |
| 别名 | Bovine adrenal medulla-22P |
| 分子式 | C130H184N38O31S2 |
| 分子量 | 2839.25 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | opium肽(opioid peptides) |
| 规格 | BAM-22P 是一种强效的opium肽，是一种强效的opium类 (opioid) 激动剂。BAM-22P, a highly potent opioid peptide, is a potent opioid agonist. |
| In Vitro | 未检测 |
| In Vivo | Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla. Plasma levels of BAM-22P are determined by a sensitive radioimmunoassay, and the specificity of the assay is confirmed using high-performance liquid chromatography. Plasma BAM-22P levels s cholestatic rats are significantly higher than those in control rats. This increase in plasma BAM-22P levels is completely prevented by adrenalectomy. Adrenal steady-state levels of proenkephalin mRNA, as determined by Northern blot hybridization analyses, are also increased significantly in cholestatic rats. These increases in proenkephalin mRNA levels are not paralleled by changes in adrenal BAM-22P peptide levels, which are similar in cholestatic rats and their respective controls. Similar levels of proenkephalin mRNA expression are observed in innervated and denervated adrenal glands from cholestatic rats, suggesting that the increase in adrenal proenkephalin mRNA levels in acute cholestasis is not due to splanchnic nerve activation. Thus acute cholestasis in the rat is associated with adrenal secretion and accumulation in plasma of the highly potent opioid peptide BAM-22P and an augmentation of adrenal proenkephalin mRNA expression. The increase in plasma BAM-22P levels may contribute substantially to the increase in total circulating opioid activity documented in cholestatic rats. Adrenal gland levels of BAM-22P are similar in BDR and sham-resected rats (BDR, 1.10±0.39 ng/g; sham, 0.93±0.16 ng/g; NS). BAM-22P levels in ANIT-treated and oil-gavaged controls are also similar (ANIT, 2.88±0.29 ng/g; control, 2.75±0.30 ng/g; NS). However, adrenal BAM-22P levels are lower in BDR and sham-resected rats than in ANIT-treated and oil-gavaged controls (P. |
| 单位 | 瓶 |
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文献和实验异硫酸酯荧光素 FLS forward light scatter 向前光散射 FN fibronectin 纤维连接蛋白 FR fast red 快红 FRA fibronection related antigen 纤维连接素相关抗原 FRC fibroblast reticulum cell 纤维母细胞性网状细胞 FSH follicle-stimulating hormone 卵泡刺激素 FTA fluorescent
by MS/MS provides the best results for phosphorylation site determination (Fig. 14). Following excision and digestion of a 32 P-labeled protein, the peptides are resolved by HPLC. By monitoring HPLC fractions for radioactivity, the phosphopeptides can be selected
[16] Li J, Wang WL, Wang WY, Liu B, Wang BY. Apoptosis in human hepatocellu lar carcinoma by terminal deoxynucleotidyl transferase mediate dUTP FITC nick end labeling.Huaren Xiaohua Zazhi,1998;6:491-494 [17] Chen GQ, Shi XG, Tang W, Xiong SM, Zhu J
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