- ￥830 - 2890
- Solarbio|ActivAb
- 北京
- CLP1362
- 2025年07月29日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 保质期：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 英文名：
PKCδ Peptide Substrate
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
10mg/5mg/1mg
| 规格： | 10mg | 产品价格： | ￥2890.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥2070.0 |
| 规格： | 1mg | 产品价格： | ￥830.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.16875-11-9 |
| 单字母序列 | PPGFSPFR |
| 三字母序列 | Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg |
| 别名 | 舒缓激肽片段2-9;Bradykinin (2-9);(Des-Arg1)-Bradykinin |
| 分子式 | C44H61N11O10 |
| 分子量 | 904.04 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 溶解性 | DMSO：100 mg/mL; *超声助溶; |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 心血管研究(Cardiovascular research) |
| 规格 | Bradykinin (2-9) 是一种氨基截短的激肽肽。Bradykinin (2-9) 是由氨基肽酶 P 切割形成的一种 Bradykinin 代谢物。Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P. |
| In Vitro | The Bradykinin peptide system is a tissue-based system with potent cardiovascular and renal effects. To investigate the regulation of this system, a highly sensitive amino terminal-directed radioimmunoassay that, with high performance liquid chromatography, enables the measurement of Bradykinin-(1-7), Bradykinin-(1-8), and Bradykinin-(1-9), is developed. Together with a carboxy terminal-directed radioimmunoassay, Bradykinin peptides in rat kidney and blood are characterized. The predominant Bradykinin peptides in kidney are Bradykinin-(1-9) (~100 fmol/g wet weight of tissue) and Bradykinin-(1-7) (~70 fmol/g), with low levels of Bradykinin-(1-8) (~8 fmol/g) and Bradykinin-(4-9) (~12 fmol/g) detectable; Bradykinin-(2-9) and Bradykinin-(3-9) are below the limits of detection. In blood, the levels of Bradykinin-(1-9) are very low (~2 fmol/ml), and other Bradykinin peptides are below the limits ofdetection. Administration of the angiotensin converting enzyme (ACE) inhibitor Perindopril is associated with an approximate twofold increase in renal levels of Bradykinin-(1-8) and Bradykinin-(1-9) and a decrease in the Bradykinin-(1-7)/Bradykinin-(1-9) ratio. The amino terminal-directed radioimmunoassay is also applied to heart, aorta, brown adipose tissue, adrenal, lung, and brain. For these tissues, Bradykinin-(1-7) and Bradykinin-(1-9) are of similar abundance (16-340 fmol/g), with lower levels of Bradykinin-(1-8). |
| 单位 | 瓶 |
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