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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 保质期:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 英文名:
Activity-Dependent Neurotrophic Factor, ADNF
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
10mg/5mg/1mg
| 规格: | 10mg | 产品价格: | ¥1960.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1400.0 |
| 规格: | 1mg | 产品价格: | ¥560.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.186319-74-4 |
| 单字母序列 | DAEFRHDSGYEVHH |
| 三字母序列 | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His |
| 分子式 | C73H99N23O25 |
| 分子量 | 1698.73 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 淀粉样肽(Amyloid Peptides) |
| 规格 | The N-terminal Aβ fragments Aβ1-14, Aβ1-15, and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The presence of these small peptides is consistent with a catabolic amyloid precursor protein cleavage pathway by β-followed by α-secretase. It has been shown that Aβ1-14, Aβ1-15, and Aβ1-16 increase dose-dependently in response to γ-secretase inhibitor treatment while Aβ1-42 levels are unchanged. |
| In Vitro | 未检测 |
| 单位 | 瓶 |
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文献和实验Visualization of Peptide Secretory Vesicles in Living Nerve Cells
Analysis of real-time movements of peptidergic vesicles in live neurons provides insight into molecular mechanism(s) supporting the activity-dependent secretion of neurotrophins and neuropeptides. We examined the effect
Emotionality-Related Consequences of Early Weaning in Mice and Rats
, decreased brain-derived neurotrophic factor protein levels in the hippocampus and prefrontal cortex, and reduced bromodeoxyuridine immunoreactivity in the dentate gyrus. These results are similar to those of human psychological disorders, and suggest
Role of Apoptosis in Neurotoxicology
to heavy metal contaminants has been implicated in apoptotic cell death. This has been demonstrated with methylmercury with in vivo exposure producing apoptosis in the cerebellum and in vitro studies in PC12 cells implicating a neurotrophic factor dependent
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