- ￥560 - 1960
- Solarbio|ActivAb
- 北京
- CLP0455
- 2025年07月29日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 保质期：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 英文名：
Antimicrobial Peptide HHC-36
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
10mg/5mg/1mg
| 规格： | 10mg | 产品价格： | ￥1960.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥1400.0 |
| 规格： | 1mg | 产品价格： | ￥560.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.256447-08-2 |
| 单字母序列 | Ac-AMVSEFLKQAW |
| 三字母序列 | Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp |
| 别名 | Annexin A1 (1-11) (dephosphorylated) (human, bovine, chicken, porcine);Annexin-1 (2-12) (human, bovine, chicken, porcine; Lipocortin-1 (2-12); Calpactin II (1-11) (dephosphorylated) (human, bovine, chicken, porcine) |
| 分子式 | C63H94O17N14S1 |
| 分子量 | 1351.57 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 炎症研究(Inflammation research) |
| 规格 | Ac2-12 是一种膜联蛋白/脂皮质激素 1 (LC1) 模拟肽，可抑制嗜中性白细胞的外渗。Ac2-12 具有抗迁移作用，并在实验性炎症模型中抑制嗜中性白细胞的募集。Ac2-12, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibit neutrophil extravasation. Ac2-12 has antimigratory action and inhibits recruitment of neutrophils in experimental inflammation models. |
| In Vitro | 未检测 |
| In Vivo | Ac2-12 (i.v.; 6.7 mg/kg, ≈70 nmol per mouse), was found to mimic the actions of lipocortin 1 (LC1) and Ac2-26 in male Swiss Albino mice (10-15 g). Ac2-12 (100 μg) significantly reduces polymorphonuclear leukocyte (PMN) influx in wild-type C57BL/6 mice and is no longer active in FPR KO mice. |
| 单位 | 瓶 |
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文献和实验Antigen Design Sera Purification Tech Sheet
to generate anti-peptide antibodies, it is important to carefully consider the ultimate use for the antibody and the sequence used to ensure success. This tech sheet will briefly explore peptide selection and design, coupling strategy, and carrier proteins
. (1997) Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry 36, 3008–3017 [55] Takeshima, K. et al. (2003) Translocation of analogues of the antimicrobial peptides magainin
phase peptide synthesis. Int. J. Pept. Pro. Res. 36, 255-266 (1990). 2. Sanii B., Kudirka, R., Cho, A., Venkateswaran, N., Oliver, G.K., Olson, A.M., Tran, H., Harada, R.M., Tan, L., & Zuckermann, R.N. Shaken, not stirred: Collapsing a peptoid
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