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- 详细信息
- 技术资料
- 保存条件:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 保质期:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 英文名:
β-Hairpin Tryptophan Zipper 2 (Trpzip2), amide
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
10mg/5mg/1mg
| 规格: | 10mg | 产品价格: | ¥2520.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1800.0 |
| 规格: | 1mg | 产品价格: | ¥720.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.256447-08-2 |
| 单字母序列 | Ac-AMVSEFLKQAW |
| 三字母序列 | Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp |
| 别名 | Annexin A1 (1-11) (dephosphorylated) (human, bovine, chicken, porcine);Annexin-1 (2-12) (human, bovine, chicken, porcine; Lipocortin-1 (2-12); Calpactin II (1-11) (dephosphorylated) (human, bovine, chicken, porcine) |
| 分子式 | C63H94O17N14S1 |
| 分子量 | 1351.57 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 炎症研究(Inflammation research) |
| 规格 | Ac2-12 是一种膜联蛋白/脂皮质激素 1 (LC1) 模拟肽,可抑制嗜中性白细胞的外渗。Ac2-12 具有抗迁移作用,并在实验性炎症模型中抑制嗜中性白细胞的募集。Ac2-12, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibit neutrophil extravasation. Ac2-12 has antimigratory action and inhibits recruitment of neutrophils in experimental inflammation models. |
| In Vitro | 未检测 |
| In Vivo | Ac2-12 (i.v.; 6.7 mg/kg, ≈70 nmol per mouse), was found to mimic the actions of lipocortin 1 (LC1) and Ac2-26 in male Swiss Albino mice (10-15 g). Ac2-12 (100 μg) significantly reduces polymorphonuclear leukocyte (PMN) influx in wild-type C57BL/6 mice and is no longer active in FPR KO mice. |
| 单位 | 瓶 |
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CLP0453 β-Hairpin Tryptophan Zipper 2 (Trpzip2), amide 抗菌肽
¥720 - 2520




