P01314 Recombinant Human PCSK9
/Proprotein Convertase 9 (Val474Ile,Gly670Glu,D374Y) 细胞因子/蛋白- ￥1092 - 21120
- Solarbio
- P01314
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥3276.0 |
| 规格： | 10ug | 产品价格： | ￥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Proprotein Convertase Subtilisin/Kexin Type 9;Neural Apoptosis-Regulated Convertase 1;NARC-1;Proprotein Convertase 9;PC9;Subtilisin/Kexin-Like Protease PC9;PCSK9;NARC1 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 50mM HEPES,150mM NaCl,20%Glycerol,pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 (D374Y) is a gain of function mutant of human PCSK9 protein.Human PCSK9 is a secretory subtilase belonging to the proteinase K subfamily.PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER，the pro domain and mature chain are secreted together through noncovalent interactions.PCSK9 binds with low-density lipoprotein receptor (LDLR) and it plays a major regulatory role in cholesterol homeostasis.Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels.PCSK9 also binds to apolipoprotein receptor 2 (ApoER2)，and play a role in the neural development. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P01314 Recombinant Human PCSK9/Proprotein Convertase 9 (Val474Ile,Gly670Glu,D374Y) 细胞因子/蛋白
￥1092 - 21120
