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- Solarbio
- P01303
- 北京
- 2025年07月25日
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￥312
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥17280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥12096.0 |
| 规格： | 50ug | 产品价格： | ￥3276.0 |
| 规格： | 10ug | 产品价格： | ￥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Coagulation Factor XIII A Chain;Coagulation Factor XIIIa;Protein-Glutamine Gamma-Glutamyltransferase A Chain;Transglutaminase A Chain;F13A1;F13A |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 50 mM NaCl,5% Sucrose, 1% Tween 20 (v/v),0.3% Histidine (w/v),pH8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤ -70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade.Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits.The A subunits have catalytic function，and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules.Platelet factor XIII is composed of just 2 A subunits，which are identical to those of plasma origin.Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion，the plasma factor XIII dissociates its B subunits and yields the same active enzyme，factor XIIIa，as platelet factor XIII.This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules，thus stabilizing the fibrin clot.Factor XIII deficiency is classified into two categories: type I deficiency，characterized by the lack of both the A and B subunits; and type II deficiency，characterized by the lack of the A subunit alone.These defects can result in a lifelong bleeding tendency，defective wound healing，and habitual abortion. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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