- ￥988 - 21120
- Solarbio
- P00970
- 北京
- 2025年07月25日
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￥988
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | F9;Coagulation factor IX;Christmas factor;Plasma thromboplastin component;Coagulation factor IXa light chain;Coagulation factor IXa heavy chain |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Coagulation factor IX（F9)，is a member of the peptidase S1 family.It contains two EGF-like domains，a Gla domain and a peptidase S1 domain.It is primarily expressed in the liver and secreted in plasma.Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions，phospholipids，and factor VIIIa.Mutations in position 43 and 46 prevents cleavage of the propeptide，mutation in position 93 probably fails to bind to cell membranes，mutation in position 191 or in position 226 prevent cleavage of the activation peptide.Mutations of human F9 can result in thrombophilia and recessive X-linked hemophilia B (HEMB).An X-linked blood coagulation disorder characterized by a permanent tendency to hemorrhage，due to factor IX deficiency.It is phenotypically similar to hemophilia A，but patients present with fewer symptoms.Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Ex Vivo Stromal Cell Electroporation of Factor IX cDNA for Treatment of Hemophilia B
Hemophilia B is an X-linked genetic disorder that typically results from chronic circulating deficiency of blood coagulation factor IX (FIX) (1). While the occurrence of hemophilia B is significantly less frequent than hemophilia A (factor
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
Identification of Mutations in the Human Factor VII Gene
by activating both arms of the coagulation cascade via its action upon factors IX and X (5 ).
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