P01149 Recombinant Human GFER/HPO/FAD-linked sulfhydryl oxidase ALR 细胞因子/蛋白

P01149 Recombinant Human GFER/

HPO/FAD-linked sulfhydryl oxidase ALR 细胞因子/蛋白
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  • ¥988 - 21120
  • Solarbio已认证
  • P01149
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名FAD-linked sulfhydryl oxidase ALR;GFER;Augmenter of liver regeneration;hERV1;Hepatopoietin;GFER;ALR;HERV1;HPO
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins.GFER is widely expressed in various human tissues.They are two isoforms of this protein.Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40,a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space.The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1,resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40,while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration.GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC).S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines.
    来源E.coli
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM HCl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.
    单位

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    P01149 Recombinant Human GFER/HPO/FAD-linked sulfhydryl oxidase ALR 细胞因子/蛋白
    ¥988 - 21120