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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | FAD-linked sulfhydryl oxidase ALR;GFER;Augmenter of liver regeneration;hERV1;Hepatopoietin;GFER;ALR;HERV1;HPO |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins.GFER is widely expressed in various human tissues.They are two isoforms of this protein.Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40,a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space.The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1,resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40,while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration.GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC).S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM HCl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test. |
| 单位 | 支 |
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