Recombinant Human CCND2 (N-6His)产品图

Recombinant Human CCND2 (N-6Hi

s)
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  • ¥1217 - 21245
  • Solarbio已认证
  • 北京
  • P01263
  • 2026年08月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期:

      Upon receipt, store it immediately at -70°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days; <br>-20°C for 1 months and -70℃ for 3 months.

    • 保存条件:

      Upon receipt, store it immediately at -70°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days; <br>-20°C for 1 months and -70℃ for 3 months.

    • 英文名:

      CCND2

    • 库存:

      999

    • 供应商:

      北京索莱宝科技有限公司

    • 规格:

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1217
    规格:50ug产品价格:¥3401
    规格:500ug产品价格:¥14909
    规格:1mg产品价格:¥21245
    基因名CCND2
    别名G1/S-specific cyclin-D2; CCND2;
    蛋白号P30279
    种属Human
    宿主E.coli
    产品描述Recombinant Human Cyclin-D2 is produced by our E.coli expression system and the target gene encoding Met1-Leu289 is expressed with a 6His tag at the N-terminus.
    区间范围Met1-Leu289
    标签信息N-6His
    预测分子量35 kDa
    表观分子量35 KDa, reducing conditions
    纯度≥90% by SDS-PAGE.
    内毒素<1EU/ug as determined by LAL test.
    溶剂Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5mM DTT, pH 7.5.
    复溶Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.
    储存条件Upon receipt, store it immediately at -70°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
    2-8°C for 2-7 days;
    -20°C for 1 months and -70℃ for 3 months.
    运输条件干冰运输(需要收取干冰费)
    背景说明CCND2, also known as G1/S-specific cyclin-D2, is a member of the highly conserved cyclin family. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 is involved in a number of fundamental biological processes such as phosphorylating and inhibiting members of the retinoblastoma (RB) protein family including RB1 and regulating the cell-cycle during G1/S transition. It is also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
    细胞活性No activity experimental data, to be verified.
    ELISA活性No activity experimental data, to be verified.
    SPR/BLI活性No activity experimental data, to be verified.
    研究领域生物制药相关研究
    英文名称CCND2
    中文名称CCND2蛋白
    单位支
    规格10ug ; 50ug ; 500ug ; 1mg

    产品细节图片1
    Purity-SDS-PAGE

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