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- Solarbio
- P01153
- 北京
- 2025年07月25日
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￥1092
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Programmed cell death protein 1;hPD-1;PDCD1;CD279 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution ofPBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain.PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators.PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1，IL-4，IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway.In addition，coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer.PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance，and thus contributes to the prevention of autoimmune diseases.As a cell surface molecule，PDCD1 regulates the adaptive immune response.Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation，cytokine production，and cytolytic function. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验RNase P Ribozyme As an Antiviral Agent Against Human Cytomegalovirus
described in this chapter focus primarily on i) construction of the retroviral vector for expression of M1GS ribozymes in cultured cells, ii) generation of stable cell lines expressing ribozymes, iii) determination of the expression of M1GS RNAs in human
Staining Methods for cell death
2 mg/ml P. I. 6 ul 5 mg/ml FDA R. T. 3 min Rinse 1 X PBS leave cells in PBS. Examine cells under the scope immediately. Note: If the P.I. staining is not strong enough to be picked up easily
Colorimetric Dehydrogenase Screen Based on NAD(P)H Generation
substrate inhibition (1 ) and eliminating the need for expensive activators (2 ). In addition, dehydrogenases are involved in alcohol metabolism (3 ), and in mammalian cell growth (4 ) and cell death (5 ). Various dehydrogenases have been implicated
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