- ￥988 - 21120
- Solarbio
- P01120
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Beta-2-Microglobulin;B2M |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family.B2M component of major histocompatibility complex (MHC) class I molecules，involved in the presentation of peptide antigens to the immune system.Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis.B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells.Serum B2M concentration is increased in renal diseases，various malignant diseases and some inflammatory and autoimmune disorders.B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.The capacity to assemble into amyloid fibrils is concentration dependent.B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis.B2M might be involved in the OA (osteoarthritis) pathogenesis.Defects in B2M are the cause of hypercatabolic hypoproteinemia.Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin，probably due to rapid degradation.B2M could be a potential therapeutic target in ovarian cancer. |
| 来源 | Human Cells |
| 溶剂 | Dissolve the lyophilized protein in distilled water. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P01120 Recombinant Cynomolgus FcRn/FCGRT & B2M Heterodimer 细胞因子/蛋白
￥988 - 21120
