P01108 Recombinant Mouse Signaling Lymphocytic Activation Molecule/SLAM/CD150 细胞因子/蛋白

P01108 Recombinant Mouse Signa

ling Lymphocytic Activation Molecule/SLAM/CD150 细胞因子/蛋白
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  • ¥988 - 21120
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  • P01108
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名signaling lymphocytic activation molecule;SLAM family member 1;CD150 antigen;CD150;SLAMF1;SLAM
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Signaling lymphocyte activation molecule (SLAM),is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells,but also on the surface of activated B cells,dendritic cells,and macrophages.SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment,and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM).SLAM is thought to play an important role in adhesion between T cells and APCs and has been shown to act as a coreceptor in TCR-dependent responses.SLAM,together with CD46,is one of the two receptors for measles virus.SLAM is a cell surface receptor that,like the B cell receptor,CD40,and CD95,can transmit positive or negative signals.SLAM can associate with the SH2-containing inositol phosphatase (SHIP),the SH2-containing protein tyrosine phosphatase (SHP-2),and the adaptor protein SH2 domain protein 1A.It’s upregulated on activated B cells and CD4+ and CD8+ T cells,but downregulated on Th2 polarized cells.Also,it can Inhibits antigen receptor-mediated production of IFN-gamma,but not IL-2,in CD4-/CD8- T-cells
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    P01108 Recombinant Mouse Signaling Lymphocytic Activation Molecule/SLAM/CD150 细胞因子/蛋白
    ¥988 - 21120