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- 详细信息
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | signaling lymphocytic activation molecule;SLAM family member 1;CD150 antigen;CD150;SLAMF1;SLAM |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Signaling lymphocyte activation molecule (SLAM),is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells,but also on the surface of activated B cells,dendritic cells,and macrophages.SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment,and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM).SLAM is thought to play an important role in adhesion between T cells and APCs and has been shown to act as a coreceptor in TCR-dependent responses.SLAM,together with CD46,is one of the two receptors for measles virus.SLAM is a cell surface receptor that,like the B cell receptor,CD40,and CD95,can transmit positive or negative signals.SLAM can associate with the SH2-containing inositol phosphatase (SHIP),the SH2-containing protein tyrosine phosphatase (SHP-2),and the adaptor protein SH2 domain protein 1A.It’s upregulated on activated B cells and CD4+ and CD8+ T cells,but downregulated on Th2 polarized cells.Also,it can Inhibits antigen receptor-mediated production of IFN-gamma,but not IL-2,in CD4-/CD8- T-cells |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P01108 Recombinant Mouse Signaling Lymphocytic Activation Molecule/SLAM/CD150 细胞因子/蛋白
¥988 - 21120





