- ￥988 - 21120
- Solarbio
- P01108
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | signaling lymphocytic activation molecule;SLAM family member 1;CD150 antigen;CD150;SLAMF1;SLAM |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Signaling lymphocyte activation molecule (SLAM)，is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells，but also on the surface of activated B cells，dendritic cells，and macrophages.SLAM consists of a extracellular domain (ECD) with two Ig-like domains，transmembrane segment，and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM).SLAM is thought to play an important role in adhesion between T cells and APCs and has been shown to act as a coreceptor in TCR-dependent responses.SLAM，together with CD46，is one of the two receptors for measles virus.SLAM is a cell surface receptor that，like the B cell receptor，CD40，and CD95，can transmit positive or negative signals.SLAM can associate with the SH2-containing inositol phosphatase (SHIP)，the SH2-containing protein tyrosine phosphatase (SHP-2)，and the adaptor protein SH2 domain protein 1A.It’s upregulated on activated B cells and CD4+ and CD8+ T cells，but downregulated on Th2 polarized cells.Also，it can Inhibits antigen receptor-mediated production of IFN-gamma，but not IL-2，in CD4-/CD8- T-cells |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验prostate cancer. Four possible mechanisms by which the AR may be actively involved in the development of AI include (1) mutations in the AR (5 ,7 –11 ); (2) AR amplification (12 ,13 ); (3) ligand-independent activation of AR through other signaling
TRAF‐Mediated TNFR‐Family Signaling
) activation depends upon the E2/E3 complex Ubc13‐Uev1A/TNF receptor‐associated factor 2 (TRAF2). J. Biol. Chem. 278:15429‐15434. Shiels, H., Li, X., Schumacker, P.T., Maltepe, E
Expanding Mouse Ventricular Cardiomyocytes Through GSK‐3 Inhibition
. , Chiravuri, M. , van der Meer, P. , Feinberg, A.W. , Shi, X. , Shao, Y. , Wu, S.M. , Parker, K.K. , and Chien, K.R. 2009. Generation of functional ventricular heart muscle from mouse ventricular progenitor cells. Science 326:426‐429
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