P01103 Recombinant Mouse CD155
/PVR/Poliovirus Receptor/Nectin-Like Protein 5/NECL-5/PVS 细胞因子/蛋白- ￥988 - 21120
- Solarbio
- P01103
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Poliovirus receptor;CD155 antigen;Nectin-like protein 5;Nectin-2;Tage4 receptor;Pvr;PVR;Necl5;CD155 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse poliovirus receptor (PVR，CD155) is a type I transmembrane (TM) glycoprotein that is a member of the nectin-related family of adhesion proteins within the immunoglobulin superfamily.It binds other molecules including vitronectin，Nectin3，DNAM1，CD96，and TIGIT，but does not bind homotypically.CD155 includes a 28 aa signal sequence，a 318 aa extracellular domain (ECD) with one N-terminal V-type and two C2-type Ig-like domains，a 24 aa TM segment and a 38 aa cytoplasmic tail.Epithelial，endothelial，and many immune cells show low CD155 expression.It is up-regulated on endothelia by IFNγ，and is highly expressed on immature thymocytes，lymph node dendritic cells，and tumor cells of epithelial and neuronal origin.On migrating cells，it is concentrated at the leading edge，where it binds basement membrane vitronectin，recruits Nectin-3-expressing cells，and cooperates with PDGF and integrin αvβ3 to promote cell migration.Binding of monocyte DNAM-1 to endothelial cell CD155 promotes transendothelial migration.Enhanced CD155 expression in tumor cells contributes to loss of contact inhibition and increased migration，but also allows tumor cell recognition and killing by DNAM-1or CD96 expressing NK cells. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验., Schroder, W., Zirngibl, H. and Nieswandt, B. (2000). Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies . Blood 95(3): 886-93. Bizzaro, N. and Fiorin, F. (1999
viral immunity pathogenesis group
., Schroder, W., Zirngibl, H. and Nieswandt, B. (2000). Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies . Blood 95(3): 886-93. Bizzaro, N. and Fiorin, F. (1999
Mouse Strains and Genetic Nomenclature
. Biol. J. Linnean Soc. 30:51‐58. Bulfield, G., Siller, W.G., Wight, P.A., and Moore, K.J. 1984. X chromosome‐linked muscular dystrophy (mdx) in the mouse. Proc. Natl. Acad
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