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- Solarbio
- P01101
- 北京
- 2025年07月25日
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￥936
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | CD226 antigen;platelet and T cell activation antigen 1;CD226 molecule;DNAM1 adhesion glycoprotein;DNAM-1;DNAX accessory molecule-1;DNAX accessory molecule 1;PTA1;T lineage-specific activation antigen 1 antigen;CD226;PTA1;TLiSA1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse DNAX accessory molecule-1(DNAM-1) is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily.As an activating receptor，it interacts with the ligands CD155 and CD112，and activates natural killer (NK) cells via its immu-noreceptor tyrosine-based activatory motif (ITAM).Mature mouse DNAM-1 has extracellular domain (ECD) that contains two Ig-like C2-set domains，and possesses a cytoplasmic region that contains motifs for binding PDZ domains.DNAM-1 is expressed on several lymphoid and myeloid cell types and interacts with CD155/PVR and Nectin-2/CD112.Ligation of DNAM-1 promotes the activation of NK cells，CD8+ T cells，and mast cells，induces dendritic cell maturation，initiates megakaryocyte and activated platelet adhesion to vascular endothelial cells，and stimulates monocyte extravasation.Conversely，it inhibits the formation of osteoclasts.Platelet-endothelium interactions that are mediated by DNAM-1 enable the metastasis of tumor cells to the lung. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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