Recombinant Mouse VISTA (C-6His)产品图

Recombinant Mouse VISTA (C-6Hi

s)
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  • ¥988 - 21120
  • Solarbio已认证
  • 北京
  • P01100
  • 2026年08月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期:

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 保存条件:

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 英文名:

      VISTA

    • 库存:

      999

    • 供应商:

      北京索莱宝科技有限公司

    • 规格:

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥988.00
    规格:50ug产品价格:¥2600.00
    规格:500ug产品价格:¥14784.00
    规格:1mg产品价格:¥21120.00
    基因名VISTA
    别名Platelet receptor Gi24; stress induced secreted protein 1; Dies1; VISTA; SISP1; B7-H5; PD-1H; GI24
    蛋白号Q9D659
    种属Mouse
    宿主HEK293
    产品描述Recombinant Mouse Platelet Receptor Gi24 is produced by our Mammalian expression system and the target gene encoding Phe33-Ala191 is expressed with a 6His tag at the C-terminus.
    区间范围Phe33-Ala191
    标签信息C-6His
    预测分子量30-40 kDa
    表观分子量30-40 KDa, reducing conditions
    纯度≥95% by SDS‐PAGE.
    内毒素<1EU/ug as determined by LAL test.
    溶剂Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    复溶Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.
    储存条件Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
    2-8°C for 2-7 days under sterile conditions after redissolves;
    -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves;
    -20°C to -70℃ for 12 months in lyophilized state.
    运输条件冷冻运输
    背景说明Mouse Platelet receptor Gi24(VISTA) is a transmembrane glycoprotein with homology to B7like immune costimulatory molecules. Mature mouse Gi24 contains a 159 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane segment, and a 97 aa cytoplasmic domain. VISTA promotes both MT1-MMP expression and the MT1-MMP mediated activation of MMP-2. It supports the differentiation of embryonic stem cells (ESC) and enhances BMP-4 induced signaling in ESC, but it is also down-regulated following BMP-4 exposure. It binds to BMP-4 directly and also associates with the type I BMP receptor Activin RIB/ALK-4. It is expressed on the surface of na ve CD4+ T cells and regulatory T cells. It is up-regulated in vivo on activated monocytes and dendritic cells. VISTA inhibits CD4+ and CD8+ T cell proliferation and their production of IL-2 and IFN-γ. Its expression on tumor cells attenuates the antitumor immune response and enables more rapid tumor progression.
    细胞活性No activity experimental data, to be verified.
    ELISA活性No activity experimental data, to be verified.
    SPR/BLI活性No activity experimental data, to be verified.
    研究领域生物制药相关研究
    英文名称VISTA
    中文名称VISTA蛋白
    单位支
    规格10ug ; 50ug ; 500ug ; 1mg

    产品细节图片1
    Purity-SDS-PAGE

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