- ￥988 - 21120
- Solarbio
- P01100
- 北京
- 2025年07月25日
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￥988
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Platelet receptor Gi24;stress induced secreted protein 1;Dies1;VISTA;SISP1;B7-H5;PD-1H;GI24 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse Platelet receptor Gi24(VISTA) is a transmembrane glycoprotein with homology to B7like immune costimulatory molecules.Mature mouse Gi24 contains a 159 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain，a 21 aa transmembrane segment，and a 97 aa cytoplasmic domain.VISTA promotes both MT1-MMP expression and the MT1-MMP mediated activation of MMP-2.It supports the differentiation of embryonic stem cells (ESC) and enhances BMP-4 induced signaling in ESC，but it is also down-regulated following BMP-4 exposure.It binds to BMP-4 directly and also associates with the type I BMP receptor Activin RIB/ALK-4.It is expressed on the surface of native CD4+ T cells and regulatory T cells.It is up-regulated in vivo on activated monocytes and dendritic cells.VISTA inhibits CD4+ and CD8+ T cell proliferation and their production of IL-2 and IFN-γ.Its expression on tumor cells attenuates the antitumor immune response and enables more rapid tumor progression. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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