P01093 Recombinant Human HER2/CD340/ERBB2/Receptor Tyrosine-Protein Kinase ErbB-2 细胞因子/蛋白

P01093 Recombinant Human HER2/

CD340/ERBB2/Receptor Tyrosine-Protein Kinase ErbB-2 细胞因子/蛋白
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  • ¥988 - 21120
  • Solarbio已认证
  • P01093
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名Receptor tyrosine-protein kinase erbB-2;Metastatic lymph node gene 19 protein;Proto-oncogene Neu;Tyrosine kinase-type cell surface receptor HER2;ERBB2;MLN19;NGL;TKR1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein,and belongs to the epidermal growth factor (EGF) receptor family.HER2 plays a key role in development,cell proliferation and differentiation.HER2 has been reported to associate with malignancy and a poor prognosis in numerous carcinomas,including breast,prostate,ovarian,lung cancers and so on.HER2 is activated by dimerization and not activated by EGF,TGF-alpha and amphiregulin.Interaction with PTK6 increases its intrinsic kinase activity.It is heterodimer with EGFR,ERBB3 and ERBB4.HER2 associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription.It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC.And also it involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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