- ￥988 - 21120
- Solarbio
- P01088
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-lymphocyte activation antigen CD80;Activation B7-1 antigen;B7;CD80 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Cluster of Differentiation 80，also called B7-1，is a member of cell surface immunoglobulin superfamily which plays key，yet distinct roles in the activation of T cells.B7-1/CD80 and B7-2/CD86，together with their receptors CD28 and CTLA4，constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses.CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells，macrophages and dendritic cells.Although both CTLA-4 and CD28 can bind to the same ligands，CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验(Functional Gene Grouping): B-cell activation: Antigen dependent B-cell activation: CD28, CD4, CD80, HLA-DRA, IL10, IL2, IL4, TNFRSF5, TNFRSF6, TNFSF5, TNFSF6. Other genes involved in B-cell activation: BLR1, HDAC4, HDAC5, HDAC7A, HDAC9, ICOSL, IGBP
immune activation, as judged by CD25 expression. REFERENCE 37 (bases 1 to 1600) AUTHORS Guo,J.S., Cho,C.H., Wang,W.P., Shen,X.Z., Cheng,C.L. and Koo,M.W. TITLE Expression and activities of three inducible enzymes in the healing of gastric ulcers
methodologies the oligonucleotide is phosphorylated at the 5' end with radiolabeled g32 P-ATP and T4 polynucleotide kinase . The probe is then incubated with individual phage plaques which have been fixed onto nitrocellulose and their DNA denatured
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