- ￥988 - 21120
- Solarbio
- P01042
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-cell surface glycoprotein CD5;CD5;CD5 antigen;CD5 antigen (p56-62);CD5 molecule;LEU1T-cell surface glycoprotein CD5;Lymphocyte antigen T1;Leu-1;T1;Ly-1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD5 is a transmembrane glycoprotein of the conserved scavenger receptor cysteine-rich (SRCR) superfamily and expressed on thymocytes，peripheral T cells and a subset of B cells (B1-a).Moreover，CD5 also was found expressed in small lymphocytic lymphoma，hairy cell leukaemia and mantle cell lymphoma cells.The long cytoplasmic tail of CD5 has no intrinsic enzymatic activity，but contains four tyrosine phosphorylation sites，including an immunoreceptor tyrosine-based (ITAM)-like motif (pseudo-ITAM) and an immunoreceptor tyrosine-based inhibitory (ITIM)-like motif (pseudo-ITIM)，as well as multiple potential serine and threonine phosphorylation sites.It physically associates with the T cell antigen receptor (TCR) and B cell antigen receptor (BCR)，where it negatively modulates the activation and differentiation signals transduced by these receptors.CD5 also plays an important role in protection from activation-induced cell death and in the recognition of pathogen associated molecular patterns (PAMPS) present on fungal surfaces. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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. Biol. J. Linnean Soc. 30:51‐58. Bulfield, G., Siller, W.G., Wight, P.A., and Moore, K.J. 1984. X chromosome‐linked muscular dystrophy (mdx) in the mouse. Proc. Natl. Acad
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