- ￥988 - 21120
- Solarbio
- P01039
- 北京
- 2025年07月25日
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￥988
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Hepatitis A virus cellular receptor 2 homolog;HAVcr-2;T-cell immunoglobulin and mucin domain-containing protein 3;T-cell immunoglobulin mucin receptor 3;T-cell membrane protein 3;Tim3;Timd3 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | T cell immunoglobulin and mucin domain-3 (TIM3)，also called hepatitis A virus cellular receptor 2 (HAVCR2)，is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response.TIM3 is expressed on the Th1 cells，CD8 T-cells，monocytes，and dendritic cells，but not on Th2 cells.TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine.Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity.Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells.TIM3 is also regarded as a potential target molecule for immunotherapy.TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses，have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P01039 Recombinant Mouse TIM-3/Havcr2 细胞因子/蛋白
￥988 - 21120
