- ￥832 - 21120
- Solarbio
- P00776
- 北京
- 2026年08月13日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2288.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Poliovirus Receptor-Related Protein 2;Herpes Virus Entry Mediator B;Herpesvirus Entry Mediator B;HveB;Nectin-2;CD112;PVRL2;HVEB;PRR2 |
| 中文名称 | Recombinant Human CD112/Nectin-2/Pvrl2/Pvr/Mph/Pvs |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily.It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region.The V domain is believed to mediate nectin binding to its ligands.Nectin2 is known to bind the pseudorabies virus，and herpes simplex virus2 (HSV2)，involving in cell to cell spreading of these viruses.It does not bind poliovirus.As a homophilic adhesion molecule，CD112 is found concentrated in adherens junctions，and exists on neurons，endothelial cells，epithelial cells and fibroblasts.CD112 has been identified as the ligand for DNAM-1 (CD226)，and the interaction of CD226/CD112 mediates cytotoxicity and cytokine secretion by T and NK cells.The costimulatory responses may be a critical component in allergic reactions and may therefore become targets for anti-allergic therapy. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验a look from the following website just by clicking "Tyrosine Phosphorylation and Dimerization" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-43F85YV-2&_user=1111158&_coverDate=06%2F29%2F2001&_rdoc=1&_fmt=full&_orig=search
() #交换 x 轴和 y 轴> p + ylim(0,15) #如果想截取某一段可以用此命令设置值域。> p + scale_x_continuous(breaks =seq(18,34,50) ) #设置刻度线位置> p + theme(axis.text.x = element_text(angle = 90,family = "Times",face = "italic",colour = "darkred",size=rel(0.9))) # angle = 90 设置字体角度, family
Nectin-4 ADC成功之后，NECTIN家族还有哪些“宝藏成员”？
-2、Nectin-3、Nectin-4；’Necl亚群包括：Necl-1、Necl-2、Necl-3、Necl-4、Necl-5。各成员在不同研究领域中存在多种命名方式，下表汇总了各成员的常用别名（含蛋白名称、基因旧称及其他数据库编号），以便检索和文献查阅。 家族成员 别名 Nectin-1 CD111, HVEC, HLGR, PRR1, PVRL1 Nectin-2 CD112, HVEB, PRR2, PVRL2, PVRR2 Nectin
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