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- Solarbio
- P00882
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Vascular cell adhesion protein 1;Vcam1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily，the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages).IL-1 beta，IL-4，TNF-alpha and IFN-gamma induced the expression of VCAM-1.The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity.Mouse VCAM-1 is Important in cell-cell recognition.it appears to function in leukocyte-endothelial cell adhesion，and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes，and mediates both adhesion and signal transduction. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验细胞粘着分子(cell adhesion molecule, CAM)
-钙粘着蛋白、P-钙粘着蛋白、N-钙粘着蛋白；③选择素家族,如L-选择素、LEU-CAM1等。后两种家族的细胞粘着分子是钙依赖性的,而免疫球蛋白超家族则是非钙依赖性的。钙粘着蛋白家族是主要的一类粘着蛋白，分布极为广泛。
In Vitro and In Vivo Quantification of Adhesion Between Leukocytes and Vascular Endothelium
6 ). Cellular deformability affects both types of forces (7 –9 ). Two families of cell adhesion molecules (CAMs) are involved in leukocyte rolling and stable adhesion. In general, the selectins (P, L, and E) mediate rolling, while the IgG superfamily members
Specific gene silencing using small hairpin RNA (shRNA) constructs offer researchers the possibility to study the influence of a single protein in the metastatic process. The role of the cellular adhesion molecule CEACAM1 on tumour formation
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