P00875 Recombinant Mouse CD31/
PECAM-1/Platelet Endothelial Cell Adhesion Molecule 细胞因子/蛋白- ￥936 - 15360
- Solarbio
- P00875
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Platelet endothelial cell adhesion molecule;PECAM-1;CD31;Pecam1;Pecam |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Platelet endothelial cell adhesion molecule (PECAM-1，CD31) is a type I transmembrane glycoprotein adhesion molecule in the immunoglobulin superfamily.PECAM-1 is concentrated at cell junctions and is required for transendothelial migration (TEM).The extracellular domain (ECD) of PECAM-1 has ten potential N-linked glycosylation sites and six C2-type Ig-like domains，the first of which is critical for adhesion and extravasation.The cytoplasmic domain contains immunoregulatory tyrosine-based inhibitory and switch motifs (ITIM，ITSM) that mediate both inhibition and activation via phosphotyrosine-mediated engagement of SH2-containing signaling molecules.Expression is restricted to cells involved in circulation，especially endothelial cells，platelets，monocytes，neutrophils and lymphocyte subsets.PECAM-1 participates with other adhesion molecules in some functions，but is the critical molecule for TEM.Homotypic PECAM-1 adhesion in trans，combined with cycling of PECAM-1 to and from surface-connected endothelial cell vesicles，leads leukocytes across endothelial tight junctions. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验实验步骤 1. Endothelial progenitor cell isolation 1) Prior to any collection of peripheral human blood, submit your research protocol to your Institutional Review Board (IRB), and after its approval, obtain
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