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P00827 Recombinant Mouse SEMA4

D/Semaphorin-4D/CD100/Semacl2/Semaj 细胞因子/蛋白
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  • ¥936 - 15360
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  • P00827
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10080.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名SEMA4D;Semaphorin-4D;M-Sema G;Semaphorin-C-like 2;Semaphorin-J;Sema J;CD100;Semacl2;Semaj
    中文名称Recombinant Mouse SEMA4D/Semaphorin-4D/CD100/Semacl2/Semaj
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
    纯度≥90% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain,one PSI domain and one Sema domain.SEMA4D is strongly expressed in lymphoid tissues,especially in the thymus,as well as in the nervous tissues.However,SEMA4D is expressed at lower levels in testes,brain,kidney,small intestine,prostate,heart,placenta,lung and pancreas,but not in colon and liver.SEMA4D is a cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling.SEMA4D is involved in a number of fundamental biological processes such as promoting reorganization of the actin cytoskeleton,the migration of cerebellar granule cells and of endothelial cells and signaling via SRC and PTK2B/PYK2,which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.Not only these,it plays a role in axonal growth cone guidance in the developing central nervous system.Semaphorin-4D / SEMA4D may play a functional role in the immune system,as well as in the nervous system.It could induce B-cells to aggregate and improves their viability (in vitro).SEMA4D is involved in regulating dendrite and axon branching and morphogenesis and promoting interaction with PLXNB1 mediates activation of RHOA.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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