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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥18600.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥12420.0 |
| 规格: | 50ug | 产品价格: | ¥2704.0 |
| 规格: | 10ug | 产品价格: | ¥897.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | CD314;KLRK1;CD314 antigen;Killer cell lectin-like receptor subfamily K member 1;killer cell lectin-like receptor subfamily K;member 1;KLR;NK cell receptor D;NKG2-D;NKG2-D type II integral membrane protein;NKG2-D-activating NK receptor;NKG2D |
| 中文名称 | Recombinant Mouse NKG2D/CD314/NKG2-D type II Integral Membrane Protein |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family.NKG2D is expressed on natural killer (NK) cells,CD8+ alpha-beta and gamma-delta T-cells.As an activating and costimulatory receptor,it involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells.It provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells,leading to cytotoxic activity.It stimulates perforin-mediated elimination of ligand-expressing tumor cells.Signaling involves calcium influx,culminating in the expression of TNF-alpha.NKG2D participates in NK cell-mediated bone marrow graft rejection and survival of NK cells.It Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA,MICB,RAET1E,RAET1G,ULBP1,ULBP2,ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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