Recombinant Human Siglec-3 (C-Fc-6His)产品图

Recombinant Human Siglec-3 (C-

Fc-6His)
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  • ¥832 - 21120
  • Solarbio已认证
  • 北京
  • P00779
  • 2026年08月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 保存条件

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 英文名

      Siglec-3

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥832.00
    规格:50ug产品价格:¥2288.00
    规格:500ug产品价格:¥14784.00
    规格:1mg产品价格:¥21120.00
    基因名Siglec-3
    别名Myeloid Cell Surface Antigen CD33; Sialic Acid-Binding Ig-Like Lectin 3; Siglec-3; gp67; CD33; SIGLEC3
    蛋白号AAH28152.1
    种属Human
    宿主HEK293
    产品描述Recombinant Human Sialic Acid Binding Ig-like Lectin 3 is produced by our Mammalian expression system and the target gene encoding Asp18-His259 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.
    区间范围Asp18-His259
    标签信息C-Fc-6His
    预测分子量80 kDa
    表观分子量80 KDa, reducing conditions
    纯度≥95% by SDS‐PAGE.
    内毒素<1EU/ug as determined by LAL test.
    溶剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2.
    复溶Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.
    储存条件Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
    2-8°C for 2-7 days under sterile conditions after redissolves;
    -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves;
    -20°C to -70℃ for 12 months in lyophilized state.
    运输条件冷冻运输
    背景说明CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.
    细胞活性No activity experimental data, to be verified.
    ELISA活性No activity experimental data, to be verified.
    SPR/BLI活性No activity experimental data, to be verified.
    研究领域生物制药相关研究
    英文名称Siglec-3
    中文名称Siglec-3蛋白
    单位
    规格10ug ; 50ug ; 500ug ; 1mg

    产品细节图片1
    Purity-SDS-PAGE

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    图标文献和实验
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      ,往往无法真实模拟人类Siglec-8或Siglec-9在人体内的实际生物学功能。研究者须进一步评估小鼠模型所得结论向临床转化的可靠性。 从科学问题到工具选择 当您确定了研究的 Siglec 成员和应用场景后,接下来的挑战是选择能够支撑高质量数据的实验工具。研究工具的选择应直接回馈您的实验问题:   如果您的问题是“受体能否识别特定的聚糖配体”:您需要具有生物活性的重组蛋白(如 Fc 融合蛋白或构象稳定的 His 标签蛋白)。这种工具是 SPR(表面

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