- ￥832 - 21120
- Solarbio
- P00779
- 北京
- 2025年07月25日
企业认证
相关产品推荐更多 >
P00853 Recombinant Mouse IL-2 R gamma/IL-2RG/CD132/Common gamma Chain/IL-2 Rγ/CIDX 细胞因子/蛋白
￥936P01011 Recombinant Mouse Adiponectin/Acrp30/ADIPOQ 细胞因子/蛋白
￥988P01150 Recombinant Human Growth hormone/GH(Pituitary,22kD) 细胞因子/蛋白
￥988P00958 Recombinant Human Parvulin-14/PIN4 细胞因子/蛋白
￥988P00878 Recombinant Human LAG-3/CD223/Lymphocyte activation gene 3 Protein 细胞因子/蛋白
￥936
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2288.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Myeloid Cell Surface Antigen CD33;Sialic Acid-Binding Ig-Like Lectin 3;Siglec-3;gp67;CD33;SIGLEC3 |
| 中文名称 | Recombinant Human CD33/Siglec-3 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD33 is a type I Lectin belonging to the Ig superfamily.CD33 contains an N terminal Ig like V type domain，which mediates sialic acid binding，followed by one Ig like C2 type domain，a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs).Eleven human Siglecs have been characterized.Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions.They are collectively referred to as CD33 related Siglecs.CD33 related Siglecs have differential expression pattern within the hematopoietic system.They are involved in the regulation of cellular activation within the immune system.Siglec 3 expression is restricted to cells of myelomonocytic lineage.Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
-1/2）激活下游信号级联反应，进而精确调控细胞的极化状态、吞噬功能或抑制性细胞因子的分泌，是决定治疗成败的关键所在。 例如，Siglec-15虽依赖DAP12接头蛋白，却表现出抑制性功能，这种独特的信号转导特征如何在髓系细胞内部实现免疫抑制？再如，Siglec-10与CD24结合后，SHP-1/2的激活如何具体阻断吞噬突触的形成？这些问题指向了一个更深层次的科学问题：在复杂的髓系细胞信号网络中，Siglec轴如何通过分子层面的博弈，最终决定免疫微环境的走向。因此，Step 2的研究决策应聚焦于此，旨在揭示
In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing
技术资料暂无技术资料 索取技术资料
