- ￥832 - 15360
- Solarbio
- P00747
- 北京
- 2025年07月25日
企业认证
相关产品推荐更多 >
P00671 Recombinant Human Mesothelin/MPF/MSLN/CAK1/Mes 细胞因子/蛋白
￥780P00647 Recombinant Mouse NGAL/Lipocalin-2/LCN2/Neutrophil gelatinase-associated lipocalin/p25 细胞因子/蛋白
￥780P00102 Recombinant Mouse LIF/Leukemia inhibitory factor 细胞因子/蛋白
￥988P00060 Recombinant Human Interleukin-37/Il-37 细胞因子/蛋白
￥1560P00461 Recombinant Mouse IL-15RA/Interleukin-15 receptor subunit alpha 细胞因子/蛋白
￥520
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10560.0 |
| 规格： | 50ug | 产品价格： | ￥2288.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Transferrin receptor protein 1;TR;TfR;Trfr;T9;p90 |
| 中文名称 | Recombinant Human TFRC |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,5% Trehalose,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa).TFRC regulated by cellular iron levels through binding of the iron regulatory proteins，IRP1 and IRP2，to iron-responsive elements in the 3'-UTR.It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen，DR1.It Interacts with SH3BP3 and STEAP3，facilitates TFRC endocytosis in erythroid precursor cells.Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes.Endosomal acidification leads to iron release.The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.Transferrin receptor is necessary for development of erythrocytes and the nervous system.A second ligand，the heditary hemochromatosis protein HFE，competes for binding with transferrin for an overlapping C-terminal binding site.It positively regulates T and B cell proliferation through iron uptake. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
P00747 Recombinant Human TFRC 细胞因子/蛋白
￥832 - 15360
