- ￥780 - 17280
- Solarbio
- P00666
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥17280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥12096.0 |
| 规格： | 50ug | 产品价格： | ￥1872.0 |
| 规格： | 10ug | 产品价格： | ￥780.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Ectodysplasin A2 receptor;EDA-A2 receptor;EDA-A2R;Tumor necrosis factor receptor superfamily member XEDAR;Tumor necrosis factor receptor superfamily member 27;X-linked ectodysplasin-A2 receptor;EDAA2R;TNFRSF27;XEDAR;EDAR2 |
| 中文名称 | Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Tumor necrosis factor receptor superfamily member 27，also known as XEDAR and EDA2R，is a type III transmembrane protein of the TNFR superfamily.EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide.EDA2R is widely expressed，notably in embryonic basal epidermal cells and maturing hair follicles.Even though it does not contain a cytoplasmic death domain，EDA2R can associate with Fas and induce EDA-A2 dependent apoptosis.Its transcription is directly induced by p53，and it mediated cell death is p53 dependent.it is down-regulated in breast，colon，and lung cancers，particularly in cases with p53 mutations.It also plays a role in EDA-A2 induced skeletal muscle degeneration and osteoblast differentiation.Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED)，a disease typically characterized by abnormal hair，teeth and sweat glands. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P00666 Recombinant Mouse Ectodysplasin A2 Receptor/EDA2R/TNFRSF27 细胞因子/蛋白
￥780 - 17280
