P00663 Recombinant Human S100 Calcium Binding Protein B/S100B 细胞因子/蛋白

P00663 Recombinant Human S100

Calcium Binding Protein B/S100B 细胞因子/蛋白
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  • ¥780 - 17280
  • Solarbio已认证
  • P00663
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥17280.0
    规格:500ug产品价格:¥12096.0
    规格:50ug产品价格:¥1872.0
    规格:10ug产品价格:¥780.0
    基本信息
    基因名
    别名Protein S100-B;S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-binding protein B;S100b;S100 beta;S100 calcium binding protein B
    中文名称Recombinant Human S100 Calcium Binding Protein B/S100B
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明S100-B,is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family.S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft.S100-B plays an important role in neurodevelopment,differentiation,and brain construction.S100-B has neuroprotective effects,but at high concentrations S100-B is neurotoxic.Extracellular concentration of S100-B increases following brain damage,which easily penetrates into cerebrospinal fluid in brain damage and then into the blood.S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS,and the astrocytes are the major cells producing S100-B protein in gray matter,as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter.The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop,enabling timely delivery of crucial medical intervention before irreversible damage occurs.In addition,S100-B,which is also present in human melanocytes,is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
    来源E.coli
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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